Effects of Dietary Addition of Sucrose, Propylene Glycol and Tween 80 on the Performance of Transitional Holstein Cows

Sucrose, Propylene Glycol, Tween 80의 첨가가 전환기 젖소의 생산성에 미치는 영향

  • 이왕식 (축산연구소) ;
  • 김현섭 (축산연구소) ;
  • 손근남 (충남대학교) ;
  • 김용국 (충남대학교) ;
  • 이현준 (축산연구소) ;
  • 기광석 (축산연구소) ;
  • 백광수 (축산연구소) ;
  • 안병석 (축산연구소) ;
  • 아주말 칸 (축산연구소) ;
  • 하종규 (서울대학교)
  • Published : 2006.12.31


This study was conducted to evaluate the effects of dietary addition of sucrose, propylene glycol and Tween 80 (Polysorbate 80 : Non-ionic Surfactants) on pre-partum (21 d) and post-partum (21 d) nutrients intake, blood metabolites, occurrence of metabolic disorders, milk yield and its composition in Holstein cows. Two basal diets were formulated each for pre- and post-partum period. The diets were mixed daily and fed at ad libitum to transitional cows. Forty cows of similar parity and milk yield were randomly divided into four groups (ten animals in each). The cows in three groups were supplemented either with 280g of sucrose/day (SU), SU+64g propylene glycol/day (SUP) or SUP+50g Tween80/day (SUPT). The feed for the fourth group was not supplemented and this group served as control (C). Pre-partum DM, total digestible nutrients (TDN), and crude protein (CP) intake was similar in cows fed C, SU, SUP, and SUPT diets. Post-partum DM, TDN, and CP intakes were the highest with SUPT diet followed by SU, SUP and control diets. Pre-partum blood non-esterified fatty acids (NEFA) concentration was noticed significantly higher in cows fed control diet compared to those fed SU, SUP and SUPT diets. The concentration of NEFA was similar at calving and during post-partum period across cows fed different experimental diets. Blood glucose and Ca concentration during pre- and post-partum periods were not significantly different in cows fed C, SU, SUP and SUPT diets. Milk yield (kg/day) was similar in cows fed different experimental diets. However, milk fat percent and 4% fat corrected milk yield were higher in cows fed SU diet (p<0.05) followed by SUP, SUPT and C diets. One case of ketosis was recorded in cows fed control diet however its occurrence was not observed in cows fed other diets. Occurrence of retained placenta and mastitis was numerically higher in cows fed control diet compared with those fed SU, SUP and SUPT diets. In conclusion, the NIS and propylene glycol feeding along with sucrose could improve the 4% fat corrected milk and fat yield in early lactating cows with significant reduction in NEFA and metabolic disorders during transitional period.


Sucrose;PG (propylene glycol);Non-ionic surfactant (NIS);Pre- and post-partum dairy cows;Nutrients intake;Blood metabolites;Metabolic disorder; Milk yield and composition


  1. Adewuvi, A. A., Gruys, E. and van Eerdenburg, F. J. C. M. 2005. Veterinary quarterly (ISSN 0165-2176) 27(3):117-126
  2. AOAC. 1990. Official Methods of Analysis. 15th Ed. Association of Official Analytical Chemists, Washington, D. C
  3. Ballard, C. S., Mandebvu, P., Sniffen, C. J., Emanuele, S. M. and Carter, M. P. 2001. Effect of feeding an energy supplement to dairy cows pre- and postpartum on intake, milk yield and incidence of ketosis. 93(1):55-69
  4. Duncan, O. D. 1955. Multiple range and multiple F-test. Biometrics. 11:1
  5. Dyk, P. B., Emery, R. S., Liesman, J. L., Bucholtz, H. F. and Vandehaar, M. J. 1995. Prepartum nonesterified fatty acids in plasma and higher in cows developing prepartum health problems. J. Dairy Sci. 78(Suppl. 1):264 (Abstr)
  6. Grummer, R. R. 1995. Impact of changes in organic nutrient metabolism on feeding the transition dairy cow. J. Anim. Sci. 73:2820-2833
  7. Lewis, C. E., Hunt, C. W., Sanchez, W. K., Treacher, R., Pritchard, G. T. and Feng, P. 1996. Effect of direct-fed fibrolytic enzymes on the digestive characteristics of a forage-based diet fed to beef steers. J. Anim. Sci. 74:3020-3028
  8. Moe, P. W. and Tyrrell, H. F. 1972. Metabolizable energy requirements of pregnant dairy cows. J. Dairy Sci. 55:480-483
  9. Ordway, R. S., Ishler, A. and Varga, G. A. 2001. Effects of sucrose supplementation on dry matter intake, milk yield, and blood metabolites of periparturient Holstein dairy cows. J. Dairy Sci. 85:879-888
  10. $SAS^{\circledR}$ Institute Inc. 1997. SAS/STAT. User's Guide: Version 7. 4th Edition. 1997. SAS Institute Inc., Cary, NC
  11. Schingoethe, D. J., Linke, K. N., Kalscheur, K. F., Hippen, A. R., Rennich, D. R. and Yoon, I. 2004. Feed efficiency of mid-lactation dairy cows fed yeast culture during summer. J. Dairy Sci. 87:4178-4181
  12. Studer, V. A., Grummer, R. R. and Bertics, S. J. 1993. Effects of prepartum propylene glycol administration on periparturient fatty liver in dairy cow. J. Dairy Sci. 76:2931
  13. 김현섭, 정하연, 이현준, 기광석, 조용만, 안병석, 이성실. 2002. 전환기 젖소의 사료첨가제 급여가 사료섭취량, 산유량 및 대사성장애 발생에 미치는 영향. 한국동물자원과학회지. 44:561-572
  14. 이성실, 김현섭, 신기준, 정일병, 이병석, 이왕식, 김창현, 정완태. 2003. 미생물 효소분비 촉진제 및 이를 함유하는 물질. 농촌진흥청 축산연구소. 특허출원번호:2003-10-0015051
  15. Vazquez-Anon, M., Bertics, S., Luck, M. and Grummer, R. R. 1994. Peripartum liver triglyceride and plasma metabolites in dairy cows. J. Dariy Sci. 77:1521
  16. Van Soest, P. J., Robertson, J. B. and Lewis, B. A. 1991. Methods of dietary fiber, neutral detergent fiber, and nonstarch polysaccharides in relation to animal nutrition. J. Dairy Sci. 74:3582-3597
  17. National Animal Health Monitoring Survey, 1996. Animal Health Report. Dairy '96:Part III: Reference of 1996 Dairy Health and Management (n212. 1196). USDA
  18. Grum, D. E., Drackley, J. K., Younker, R. S., La Count, D. W. and Veenhuizen, J. J. 1996. Nutrition during the dry period and hepatic lipid metabolism of periparturient dairy cows. J. Dairy Sci.79:1850- 1864