Asymmetric Hydrogenation of Ethyl Pyruvate over Bimetallic Rh-Pt/Al2O3 Catalysts Modified with Dihydrocinchonidine

Dihydrocinchonidine으로 개질된 Rh-Pt/Al2O3 이원금속 촉매를 이용한 Ethyl Pyruvate의 비대칭 수소화

  • Cho, Hong-Baek (Division of Material and Chemical Engineering, Hanyang University) ;
  • Kang, Joon-seok (Division of Material and Chemical Engineering, Hanyang University) ;
  • Park, Yeung-Ho (Division of Material and Chemical Engineering, Hanyang University)
  • 조홍백 (한양대학교 재료화학공학부) ;
  • 강준석 (한양대학교 재료화학공학부) ;
  • 박융호 (한양대학교 재료화학공학부)
  • Received : 2006.03.09
  • Accepted : 2006.06.07
  • Published : 2006.08.10

Abstract

$Rh-Pt/Al_{2}O_{3}$ catalysts were used for the first time to study its reaction characteristics in the asymmetric hydrogenation of ethyl pyruvate. The catalysts were prepared either by impregnation of Rh on a commercial $Pt/Al_{2}O_{3}$ or by sequential impregnation of Rh followed by impregnation of Pt on $Al_{2}O_{3}$. Reaction rate and enantiomeric excess (ee%) were compared according to the preparation method, Rh contents, and the reduction temperature of the catalyst. The physical characteristics of the catalysts were analyzed using XRD and TEM. Bimetallic $Rh-Pt/Al_{2}O_{3}$ catalysts showed an improved reaction rate and optical purity (63.6 ee%) with increasing the reduction temperature. The variation of the Rh contents as well as the preparation method elicited a big difference on the reaction rate, while enantiomeric excess (ee%) was lower (56~60%) with all bimetallic catalysts than with monometallic $Pt/Al_{2}O_{3}$ catalyst.

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