Analysis of Influenza Virus Isolates in Seoul during 2003-2004 Season

2003-2004 절기 서울지역의 인플루엔자 바이러스 분리 및 아형 분석

  • Hwang Young-Ok (Seoul Metropolitan Goverment Research Institute of Public Health and Enviroment) ;
  • Lee Jae-In (Seoul Metropolitan Goverment Research Institute of Public Health and Enviroment) ;
  • Seo Byung-tae (Seoul Metropolitan Goverment Research Institute of Public Health and Enviroment)
  • 황영옥 (서울특별시보건환경연구원) ;
  • 이재인 (서울특별시보건환경연구원) ;
  • 서병태 (서울특별시보건환경연구원)
  • Published : 2005.03.01


Influenza is an important public health problem which occurs almost every winter in temperate climates and is often associated with increased rates of hospitalization and death. In 1999, our influenza surveillance was initiated with 4 voluntary sentinel physicians and the Public Health Center. During the 2003-2004 influenza season, 124 influenza viruses were isolated from 401 clinical specimens, which were collected from patients with Influenza-like illness(ILI) in Seoul. The case definition of ILI is a case with fever more than $38^{\circ}C$ and systemic symptoms; cough, or sore throat. ILI was the highest at the 20-49 age $group(23\%)$ and the rate of virus isolation was the highest at the 7-19 age $group(50\%)$. Among 124 influenza viruses, isolates 83 were identified as A/H3N2 type and others were subtyped as influenza B viruses in 2003-2004 season. Influenza viruses were collected $39.1\%$ at Nowon-Gu, $13.5\%$ Gangnam-Gu and Seocho-Gu etc. and the isolate rate of virus had the area difference; Yongsan-Gu $66.7\%$, Gangnam-gu $50.0\%$, Nowon-Gu $39.9\%$, Kangbuk-Gu $36.8\%$, Seocho-Gu $27.8\%$, Dongjak-Gu $21.2\%$. Out of 401 individuals, 160 was vaccinated $(40\%)$ and the vaccination rate was the highest at the 20-49 age $group(32\%)$. These findings may contribute to the recommondation of the influenza vaccine formulation and the development of influenza control measure.


A/H3N2;ILI;influenza virus;subtype;type B


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