Effect of the Radiation Crosslinking and Heating on the Heat Resistance of Polyvinyl Alcohol Hydrogels

PVA 하이드로겔의 내열특성에 방사선 가교와 열처리가 미치는 효과

  • Park, Kyoung Ran (Radiation Application Division, Korea Atomic Energy Research Institute) ;
  • Nho, Young Chang (Radiation Application Division, Korea Atomic Energy Research Institute)
  • 박경란 (한국원자력연구소 방사선이용연구부) ;
  • 노영창 (한국원자력연구소 방사선이용연구부)
  • Received : 2004.11.15
  • Accepted : 2005.03.08
  • Published : 2005.06.10


Polyvinyl alcohol (PVA) hydrogels were prepared by the irradiation and heating. Irradiation and heating processes were carried out to improve the heat resistance of PVA hydrogels at high temperature. The physical properties such as gel content, degree of swelling and gel strength for the synthesized hydrogels were examined. The structure variations were investigated using the following techniques: differential scanning calorimetry (DSC) and X-ray diffraction (XRD). Gel content and gel strength of the hydrogels were higher when the two steps of irradiation followed by heat treatment were used rather than only with the irradiation. The hydrogels prepared by the irradiation and the two steps had good heat resistance at high temperature.


Supported by : 과학기술부


  1. F. H. Silver and C. Doillon, Biocompatibility. Interactions of Biological and Implantable Materials, VCH Publ. Inc., New York (1989)
  2. N. A. Peppas, Hydrogels in Medicine and Pharmacy, ed. Boca Raton, 1, CRC Press. Inc., Florida (1986, 1987)
  3. B. D. Ralner, Biomedical Applications of Hydrogels: Review and Critical Appraisal, ed. D. F. Williams, 145, CRC Press, Boca Raton (1981)
  4. V. Kudela, Polymers: Biomaterials and Medical Applications, ed. J. I. Kroschwitz, 228, John Wiley & Sons, New York (1989)
  5. J. M. Rosiak, J. Controlled Release, 31, 9 (1994) https://doi.org/10.1016/0168-3659(94)90246-1
  6. K. R. Park and Y. C. Nho, Polymer(Korea), 25, 728 (2001)
  7. Y. C. Nho and K. R. Park, J. Appl. Polym. Sci., 85, 1787 (2002) https://doi.org/10.1002/app.10812
  8. K. R. Park and Y. C. Nho, Polymer(Korea), 26, 792 (2002)
  9. K. R. Park and Y. C. Nho, Radiat. Phys. Chem., 67, 361 (2003) https://doi.org/10.1016/S0969-806X(03)00067-7
  10. K. R. Park and Y. C. Nho, J. Appl. Polym. Sci., 91, 1612 (2004) https://doi.org/10.1002/app.13299
  11. K. Burczak, T. Fujisato, M. Hatada, and Y. Ikada, Biomaterials., 15, 231 (1994) https://doi.org/10.1016/0142-9612(94)90072-8
  12. M. Nambu, Rubber-like poly(vinyl alcohol) gel, Polym. Applic., 32, 523 (1983)
  13. S. H. Hyon and Y. Ikada, Radiation crosslinking of biomedical hydrogels, 6th Symp. on Radiation Chemistry, 657, Balatomszeplak, Hungary (1986)
  14. T. Hirai, High Polym., Japan, 40, 524 (1991)
  15. J. W. K. Sptizen, Ph.D. Dissertation, Twente University, The Netherlands (1988)
  16. C. Tranquilan-Aranilla, F. Yoshii, A. M. Dela Rosa, and K. Makuuchi, Radiat. Phys. Chem., 55, 127 (1999) https://doi.org/10.1016/S0969-806X(98)00317-X
  17. L. F. Miranda, A. B. Lugao, L. D. B. Machado, and L. V. Ramanathan, Radiat. Phys. Chem., 55, 709 (1999) https://doi.org/10.1016/S0969-806X(99)00216-9
  18. M. Krumova, D. Lopez, R. Benavente, C. Mijangos, and J. M. Perena, Polymer, 41, 9265 (2000) https://doi.org/10.1016/S0032-3861(00)00287-1
  19. R. L. Clough and S. W. Shalaby, Radiation effects on polymers, 271, Maple Press. Inc., York, PA (1990)
  20. F. Yoshii, K. Makuuchi, D. Darwis, T. Iriawan, M. T. Razzak, and J. M. Rosiak, Radiat. Phys. Chem., 46, 169 (1995) https://doi.org/10.1016/0969-806X(95)00008-L