The Changes of Reflux Symptoms and Laryngoscopic Findings in Treatment of Patients with Laryngopharyngeal Reflux

인후두 역류증의 치료 시 증상과 후두내시경 소견의 변화

  • Tae, Kyung (Department of Otolaryngology-Head and Nech Surgery, College of Medicine, Hanyang University) ;
  • Lee, Yong-Seop (Department of Otolaryngology-Head and Nech Surgery, College of Medicine, Hanyang University) ;
  • Jeong, Jin-Hyeok (Department of Otolaryngology-Head and Nech Surgery, College of Medicine, Hanyang University) ;
  • Park, In-Beom (Department of Otolaryngology-Head and Nech Surgery, College of Medicine, Hanyang University) ;
  • Lee, Seung-Hwan (Department of Otolaryngology-Head and Nech Surgery, College of Medicine, Hanyang University) ;
  • Kim, Kyung-Rae (Department of Otolaryngology-Head and Nech Surgery, College of Medicine, Hanyang University)
  • 태경 (한양대학교 의과대학 이비인후-두경부외과학교실) ;
  • 이용섭 (한양대학교 의과대학 이비인후-두경부외과학교실) ;
  • 정진혁 (한양대학교 의과대학 이비인후-두경부외과학교실) ;
  • 박인범 (한양대학교 의과대학 이비인후-두경부외과학교실) ;
  • 이승환 (한양대학교 의과대학 이비인후-두경부외과학교실) ;
  • 김경래 (한양대학교 의과대학 이비인후-두경부외과학교실)
  • Published : 2005.06.01

Abstract

Background and Objectives : To determine the changes of reflux symptoms and laryngoscopic findings of patients with laryngopharyngeal reflux (LPR) on the duration of proton pump inhibitor medication. Materials and Methods : From Feb 2003 to Nov 2004, 58 patients who were diagnosed with LPR by 24-hour double-probe pH monitoring were enrolled. All patients were treated with proton pump inhibitor and followed up for 8 weeks at least. The response of symptoms and laryngoscopic findings of patients were assessed with reflux symptom index (RSI) and reflux finding score (RFS) before treatment and 2, 4, 8, 12, 16, 20 weeks after treatment. Results : The symptoms of patients with LPR were improved significantly at 2, 4, 8 weeks of treatment. The laryngoscopic findings of patients with LPR were improved significantly at 4 and 12 weeks of treatment. There was no correlation between improvement of reflux symptoms and laryngoscopic findings. Conclusions : The laryngoscopic findings of LPR patients were improved more slowly than reflux symptoms. Based on our results, anti-reflux therapy might be continued at least for 3 months until the improvement of laryngoscopic findings.