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Effect of Water Extract of Germinated Brown Rice on Adiposity and Obesity Indices in Mice Fed a High Fat Diet

  • Oh, Suk-Heung (Department of Medicinal Biotechnology, Woosuk University, Department of Life Science and Technology, Graduate School, Woosuk University) ;
  • Moon, Yeon-Jeong (Department of Life Science and Technology, Graduate School, Woosuk University) ;
  • Soh, Ju-Ryoun (Department of Food Science and Human Nutrition, and 1nstitute for Molecular Biology and Genetics, Chonbuk National University) ;
  • Cha, Youn-Soo (Department of Food Science and Human Nutrition, and 1nstitute for Molecular Biology and Genetics, Chonbuk National University)
  • Published : 2005.09.01

Abstract

An extract obtained from germinated brown rice was evaluated for protective effects against the adverse effects of a chronic high fat diet. C57BL6/J mice were divided into three groups; normal diet + water group (ND), high fat diet + water group (HD), high fat diet + brown rice water extract group (HD + BE) and fed for 8 weeks (6 day/week). The ND group diet was 11 kcal fat $\%$. The HD group and HD + BE group diet were 42 kcal fat $\%$. Weight gains were not significantly different between groups. However, abdominal fat $\%$ was 1.6-fold higher in the HD group than HD + BE group. Feed consumption was significantly higher in the ND group than HD group. Serum triglyceride, total cholesterol and LDL-cholesterol increased with a high fat diet, but decreased by brown rice water extract administration to the high fat diet group. Serum HDL-cholesterol decreased by the high fat diet, but increased by the brown rice wate extract administration. Also, serum HDL-cholesterol/total cholesterol ratio was 2.3-fold higher in the HD + BE than the HD. Liver triglyceride and total cholesterol were not significantly different among groups. These data suggest that brown rice water extract administration improves the serum lipid profiles of C57BL/6J mice.

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