Isolation of Pigment Overproducing Mutant from Monascus purpureus and Optimization of Pigment Production

Monascus purpureus로부터 다량의 색소생성 변이주의 분리 및 색소생성의 최적조건

  • Park Chi Duck (Department of Microbiology, Keimyung University) ;
  • Jung Hyuck Jun (Department of Microbiology, Keimyung University) ;
  • Yu Tae Shick (Department of Microbiology, Keimyung University)
  • 박치덕 (계명대학교 미생물학과) ;
  • 정혁준 (계명대학교 미생물학과) ;
  • 유대식 (계명대학교 미생물학과)
  • Published : 2005.06.01

Abstract

Isolation of a pigment overproducing mutant, P-57, by ultraviolet irradiation of Monascus purpureus KCCM 60016 and investigation of the optimal conditions for pigment production of the mutant were carried out. P-57 mutant produced pigment on solid state culture. Unpolished rice was the best cereal source for pigment production among eight kinds of tested cereal sources for the solid culture of the mutant. The optimal culture condition for pigment production were obtained from the cultivated at $30^{\circ}C,\;90\%$ humidity for 30 days. The P-57 mutant strain showed the best pigment productivity of 160.0 unit at red pigment, 193.6 unit at orange pigment, and 141.6 unit at yellow pigment on solid state culture under optimal condition.

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