- Volume 13 Issue 2
Studies of CheongSimYeonJaTang that get weight, hematology, biochemistry change by Wistar rat's aging
청심연자탕(淸心蓮子湯)이 Wistar rat의 노화에 따른 체중, 혈액학적 및 혈청 생화학적 변화에 관한 실험적(實驗的) 연구(硏究)
- Ju, Lip-San (Dept. of Sasang Constitutional Medicine, College of Oriental Medicine, Daejeon Univ.) ;
- Ahn, Taek-Won (Dept. of Sasang Constitutional Medicine, College of Oriental Medicine, Daejeon Univ.)
- Accepted : 2004.10.14
- Published : 2004.12.30
Using aged Wistar rat living body change by aging CheongSimYeonJaTang was each orally administrated and achieved research about aging control. In Wistar rat 10, 30, 50 week and 40 week CheongSimYeonJaTang between 10 weeks form condition change of weight, change of intestine weight, hematology, blood chemistry, research result about serum content following conclusion get. 1. Observed gain in weight than control group form of CheongSimYeonJaTang to aged Wistar rat. 2. Is thought to promote activation of living body action gaining intestine weight along with gain in weight. 3. Displayed decrease of MDA's content of serum than control group form of CheongSimYeonJaTang to aged Wistar rat. 4. Change that is Wistar rat's hematological value by aging according to 10, 30, 50 week WBC, RBC, Hgb, monocytes, eosinophil etc. increase, and HCT, PLT etc. showed tendency that decrease according to old-week, and observed improvement that is hematological value than control group form of CheongSimYeonJaTang. 5. Change that is Wistar rat's biochemical value by aging was measured highest in 50 week because ALT, AST, BUN, CRN, T-bili., T-chol, TG, TP, ALB, A/G, P etc. increase according to 10, 30, 50 week, and observed improvement that is biochemical value than control group form of CheongSimYeonJaTang. Is considered by being effect that CheongSimYeonJaTang living body function decline by aging by this result.