DOI QR코드

DOI QR Code

Effects of Calcium Lactate and Chungkukjang on Calcium Status in Rat

  • Lee, Ye-Kyung (Department of Food Science and Technology, Catholic University) ;
  • Lee, Myung-Ye (Department of Food Science and Technology, Catholic Universit) ;
  • Kim, Mee-Kyung (Department of Hotel Culinary Art, Moonkyung Colleg) ;
  • Choe, Won-Kyung (Division of Food Science, Gimcheon Colleg) ;
  • Kim, Soon-Dong (Department of Food Science and Technology, Catholic University)
  • Published : 2004.03.01

Abstract

Effects of dietary calcium lactate (CaL-A) and Chungkukjang (Korean native fermented soybean) on bone mass, calcium status, body weight, serum glucose and cholesterol levels in young male rats were investigated. Chungkukjang was fermented by mixing 4 types of Bacillus sp., and then dried at 45$^{\circ}C$. Calcium lactate was prepared from the ash of black snail. The rats were fed a commercial rat diet for 1 week and then the experimental diets for 4 weeks. Animals were divided into four dietary groups: one calcium-deficient diet (Ca-De) and one of three with calcium supplemented diets (5 g calcium/kg diet) with either calcium phosphate (Ca-P), CaL-A, or CaL-A + Chuntkukjang (CaL-AC). Calcium supplemented diets contained 39 g Ca-P/kg diet and 28 g/kg of calcium lactate in the CaL-A and CaL-AC diets. Body weight gains during the 4 weeks in the Ca-P, CaL-A, CaL-AC and Ca-De groups were 130.45 g,112.50 g, 143.40 g and 10.20 g, respectively. Feed consumption of the groups from high to low was CaL-AC > Ca-P > CaL-A > Ca-De. The Ca-De group had low femur weights and low serum calcium concentrations, while they were comparatively high in CaL-AC, Ca-P and CaL-A groups. The Ca-De groups excreted less calcium in urine than did the other rats, probably due to increased absorption of the mineral in Ca-P, CaL-A and CaL-AC groups. Microscopic observations revealed that there were many regularly spaced holes in the femur of Ca-De group, while there were much smaller regularly spaced holes in Ca-P group. However, no holes in femur were observed in the CaL-A and CaL-AC groups. Bone surfaces were especially smooth and clean in the CaL-AC group. Serum concentrations of glucose and total cholesterol were remarkably lower in the CaL-AC group than in the other supplemented groups. These results suggest that calcium from CaL-A has higher bioavailability than from Ca-P, and dietary Chungkukjang may have a beneficial effect on calcium metabolism.

References

  1. Am J Clin Nutr v.35 Calcium bioavailability and absorption: A review Allen LH
  2. Korean J Food Sci Technol v.28 Preparation of calcium-for-tified soymilk and in vitro digestion properties of its protein and calcium Pyun JW;Hwang IK
  3. Korean J Nutr v.34 The effect of habitual calcium and sodium intakes on blood presure regulating hormone in free-living hypertensive women Park JA;Yoon JS
  4. Caries Res v.19 Effect of calcium lactate and calcium lactophosphate on caries activity in programmefed rats Van Der Hoeven JS https://doi.org/10.1159/000260868
  5. Cereal Chem v.74 Bioavailability of calcium in breads fortified with differenct calcium sources Ranhotra GS;Gelroth JA;Leinen SD;Schneller FE https://doi.org/10.1094/CCHEM.1997.74.4.361
  6. Acta Biotechnol v.9 Enrichment of soybean milk with calcium Prabharaksa C;Olek AC;Steinkraus KH https://doi.org/10.1002/abio.370090103
  7. J Food Prot v.64 Survival of Salmonellae in pasteurized, refrigerated calcium-fortified orange juice Sharma M;Beuchat LR;Doyle MP;Chen J
  8. Inter Dairy J v.7 Fortification of yoghurt with calcium salts and its effect on starter microorganisms and yoghurt quality Pirkul T;Temiz A;Erdem YK https://doi.org/10.1016/S0958-6946(97)00030-7
  9. Nutraceuticals & Food v.8 Preparation and charateristics of calcium lactate from black snail Lee YK;Kim SD https://doi.org/10.3746/jfn.2003.8.2.166
  10. J Food Prot v.57 Antimicrobial effects of lactates, a review Shelef LA
  11. J Nutr v.124 Bone repair in calcium-deficient rats: comparison of xylitol + calcium carbonate with calcium carbonate, calcium lactate and calcium citrate on the repletion of calcium Hamalainen MM
  12. Caries Res v.16 Preliminary studies on calcium lactate as an anticaries food additive Shrestha BM;Mundorff SA;Bibby BG https://doi.org/10.1159/000260570
  13. Eur J Cancer v.34 Calcium inhibits colon carcinogenesis in an experimental model in the rat Vinas-Salas J;Biendicho-Palau P;Pinol-Felis C;Miguelsanz-Garcia S;Perez-Holanda S https://doi.org/10.1016/S0959-8049(98)00197-X
  14. Korean J Food Sci Technol v.23 Physico-chemical properties of viscous substance extrated from Chungkukjang Lee BY;Kim DK;Kim KH
  15. Kor J Appl Microbiol Biotechnol v.23 Screening and identification of the fibinolytic bacterial strain from Chungkook-jang Kim YT;Kim WK;Oh HI
  16. Food Ind Nutr v.4 Physiologica functions of Chongkukjang Kim SH;Yang JL;Song YS
  17. Korean J Nutr v.29 The effect of various types of calcium sources on calcium and bone metabolism in rats Chung HK;Chang NS;Lee HS;Jang YE
  18. Korean J Nutr v.28 Effects of bovine bone ash and calcium phosphate on calcium metabolism in postmenopausal osteoporosis model rats Lee YS;O JH
  19. J Nutr v.117 Mineral utilization by rats fed various commercially available calcium supplements or milk Greger JL;Catherine EK;Reen RK;Connie LK
  20. Korea J Vet Res v.40 The changes of osteocalin, bone-specific alkaline phosphatase, estrogen, IGF-I, Ca2+ , P and bone mineral density on osteoporosis induced by ovariectomy in rats Kim NS;You YS;Kang CW;Chio IH
  21. Am J Clin Nutr v.50 Calcium supplementation and bone loss in middle aged women Smith EL;Gilligan C;Smith PE;Sempos CT
  22. Korean J Nutr v.26 Effects of dietary calcium levels on the reduction of calcium availability in ovariectomized osteoporosis model rats O JH;Lee YS
  23. The Korean Nutr Soc v.30 The effect of dietary calcium and phosphate levels on calcium bone metabolism in rats Jeong HK;Kim JY;Lee HS
  24. Am J Obster Gynecol v.156 Estrogen therapy in prevention and management of osteoporosis Lindsay R https://doi.org/10.1016/0002-9378(87)90177-3
  25. Acta Orthopedica Scandinavica v.57 Bone changes after castration in rats; A model for osteoporosis Gurkan L;Ekland A;Gautvik KM;Langelland N;Roenningen H;Solheim LF https://doi.org/10.3109/17453678608993219
  26. J Korean Fish Soc v.31 Effect of calcium compounds from oyster shell bounded fish skin gelatin peptide in calcium deficient rats Kim GH;Jeon YJ;Byun HG;Lee YS;Lee EH;Kim SK
  27. Korean J Nutr v.33 Effect of excess calcium and iron supplement on bone loss, nephrocalcinosis and renal function in osteoporotic model rat Lee JH;Lee YS
  28. Curr Diab Res v.3 Osteoporosis and Diabetes Chau DL;Edelman SV;Chandran M https://doi.org/10.1007/s11892-003-0051-8
  29. Endorc J v.42 Effect of glycemic control on calcium and phosphorus handling and parathyroid hormone level in patients with non-insulin-dependent diabetes mellitus Nagasaka S;Murakami T;Uchikawa T;Ishikawa SE;Saito T
  30. Diabet Med v.10 Calcium metabolism in diabetes mellitus: effect of improved blood glucose control Thalassinos NC;Hadjiyanni P;Tzanela M;Alevizaki C;Philokiprou D https://doi.org/10.1111/j.1464-5491.1993.tb00076.x

Cited by

  1. Preparation of Cheonggukjang added onion (Allium cepa L.) and its antioxidative activity vol.21, pp.1, 2014, https://doi.org/10.11002/kjfp.2014.21.1.46