- Volume 17 Issue 8
DOI QR Code
Effect of Sheep and Chicken Antibodies to Rat Adipocytes Plasma Membranes on Rat Carcass Fat
- Wang, Jundong (Shanxi Key Lab. of Ecological Animal Science and Environmental Veterinary Medicine Shanxi Agricultural University) ;
- Zhang, Jianfeng (Shanxi Key Lab. of Ecological Animal Science and Environmental Veterinary Medicine Shanxi Agricultural University) ;
- Li, Junping (Shanxi Key Lab. of Ecological Animal Science and Environmental Veterinary Medicine Shanxi Agricultural University) ;
- Hao, Junhu (Shanxi Key Lab. of Ecological Animal Science and Environmental Veterinary Medicine Shanxi Agricultural University) ;
- Wang, Shaolin (College of Veterinary Medicine, China Agricultural University) ;
- Zhang, Jianhai (Shanxi Key Lab. of Ecological Animal Science and Environmental Veterinary Medicine Shanxi Agricultural University)
- Received : 2003.12.02
- Accepted : 2004.04.29
- Published : 2004.08.01
Polyclonal anti-sera were collected from sheep and chicken immunized with adipocytes plasma membranes. Thirty two male wistar rats, weighing 185-215 grams, were divided randomly into 4 groups (trial 1: control group and treat group, trial 2: control group and treat group), with 8 rats in each group. The experiment lasted for 7 weeks. Trial one: The control group received four consecutive daily intraperitoneal injections of 1ml of sheep normal sera. The same 4 day daily dose of group sheep anti-rats sera adipocyte plasma membrane anti-sera was administered to the treat group. The results showed that the treatment for treat group increased body weight by 6.35% (p<0.05) and food intake by 6.85%, and improved food conversion efficiency (Food intake/gain) by 45.00% (p<0.05). Periernal, epididymal and omental adipose deposit weights were decreased by 23.92% (p<0.05), 34.45% (p<0.05) and 0.98% respectively, while total fat content decreased by 20.92%. Trial two: The control group received four consecutive daily intraperitoneal injections of 1 ml of chicken normal sera, the results of injections of chicken anti-rats sera adipocyte plasma membrane antis-era administered to the treat group indicated that chicken anti-rats adipocyte plasma membranes immunization had an disadvantageous effect on the growth of the wistar rats by the end of 7th wk, compared with the control group. The immunized group decreased in total weight by 40 gram (p<0.05) an averagely and in food intake noticeably (p<0.01). The deposition of fat and the rates of TG and FFA in serum had no statistical significance.
- Hu, C. Y., A. Suryawan and J. Killefer. 1992. Effect of antiserum to rat adipocytes on growth and body composition of the rat. Comp. Biochem. Physuil. 101A:669.
- Kim, Y. M., J. H. Kim, S. C. Kim, H. M. Ha, Y. D. Ko and C. H. Kim. 2002. Influence of dietary addition of dried wormwood (Artemisia sp.) on the performance, carcass characteristics and fatty acid composition of muscle tissues of Hanwoo heifers. Asian-Aust. J. Anim. Sci. 15(4):549-554.
- Wang, Jundong, Li Junping, Zhang Jianfeng and Hao Junhu. 2004. Effect of Betaine Supplement in Different Growing Stages on Broiler Performance and Fat Distribution. Chin. J. Vet. Med. 24:87-91.
- Xi, G., Z. R. Xu and P. Xiao. 2002. Growth associated hormones response and fat metabolism change in finishing pigs fed with n-methyl-d, l-aspartate. Asian-Aust. J. Anim. Sci. 15(7):1026-1030.
- Shim, K. S., G. H. Park and C. J. Choi. 2004. Decreased triglyceride and cholesterol levels in serum, liver and breastmuscle in broiler by the supplementation of dietary codonopsis lanceolata root. Asian-Aust. J. Anim. Sci. 17:511-513.
- Moloney, A. P., P. Allen and W. J. Enright. 1989. Growth and weight of abdominal and carcass fat in sheep immunized against adipose cell membranes [J]. Proc. Nutr. Soc. 48:14A.
- Wang, Jundong, Du Rong, Qin Jian Wang Shaolin, Wenkui Wang, Hongquan Li and Quanhai Li. 2003. Effect of L-carnitine and Yeast Chromium on Lipid Metabolism of Broiler Chickens. Asian-Aust. J. Anim. Sci. 16:1809-1815.
- Nassar, A. H. and C. Y. Hu. 1991. Growth and carcass characteristics of lambs passively immunized with antibodies developed against ovine adipocytes plasma membranes. J. Anim. Sci. 69:578-586.
- Wang, Jundong, Li Shuqin, Shen ruiling and Hao Junhu. 2003. Effects of Different Traditional Chinese Medicine Compounds on Lipid Metabolism, Production Performance and Meat Quality in Broiler. Chin. J. Vet. Med. 23:377-379.
- Panton, D., C. Futter and S. Kestin. 1990. Increased growth and protein deposition in rats treated with antibodies to adipocytes [J]. Am. J. Phy. 258:E985-989.
- Lien, Tu Fa, Jan Derfang and T. F. Lien. 2003. Enzyme activities realted to lopid metabolism in the liver and adipose tissue of Tsaiya ducks underfasting and ad libitum feeding condition. Asian-Aust. J. Anim. Sci. 16:403-408.
- Kestin, S., R. Kennedy, E. Tonner and M. Kiernan. 1993. Decreased fat content and increased lean in pigs treated with antibodied to adipocytes plasma membranes [J]. J. Anim. Sci. 71:1486-1494.
- Loh, T. C., H. L. Foo, B. K. Tan and Z. A. Jelan. 2002. Effects of palm kernel cake on performance and blood lipids in rats. Asian-Aust. J. Anim. Sci. 15(8):1165-1169.
- Marks, H. L. and K. W. Washburn. 1997. Divergent selection for yolk cholesterol in laying hen [J]. Br. Poult. Sci. 18:179-188.
- Moloney, A. P., P. Allen and W. J. Enright. 1998. Passive immunization against adipose tissue: Effect on metabolism growth and body composition [J]. Livestock Production Science 56:233-244.
- Wang, Wenjun, Huang Lusheng and Gao Jun. 2003. Polymorphism of growth hormone gene in 12pig breeds and its relationship with pig growth and carass traits. Asian-Aust. J. Anim. Sci. 16:161-164.
- Dulor, J. P., Y. Reyne and J. Nougues. 1990. In vivo effects of a treatment with antibodies to adipocytes plasma membranes in the rabbit [J]. Reproduction Nutrition Development 30:49-58.