A Comparison of Two Kinds of Markers Applied in Analysis of Genetic Diversity in Sheep and Goat Populations

  • Yang, Z.P. (Animal Science and Technology College, Yangzhou University) ;
  • Chang, H. (Animal Science and Technology College, Yangzhou University) ;
  • Sun, W. (Animal Science and Technology College, Yangzhou University) ;
  • Gen, R.Q. (Animal Science and Technology College, Yangzhou University) ;
  • Mao, Y.J. (Animal Science and Technology College, Yangzhou University) ;
  • Tsunoda, K. (Showa University School of Medicine)
  • Received : 2003.04.29
  • Accepted : 2004.03.16
  • Published : 2004.07.01


A genetic examination using 14 structural loci and 7 microsatellite markers was carried out among random samples of Hu sheep (Hu), Tong sheep (Tong) and Yantse River Delta White goat (YRD); The mean heterozygosity (H), mean polymorphism information contents (PIC) and mean effective numbers of alleles (Ne) calculated based on the data from the above two types of genetic markers were compared. The standard genetic distances among the three populations based on two types of gene frequencies were calculated and compared. The results show that the mean heterozygosity (H), mean polymorphism information contents (PIC) and mean effective numbers of alleles (Ne) based on 7 microsatellite markers are greater than those based on the structural loci. The standard genetic distances based on structural loci among the three populations are: 0.0268-0.2487, the standard genetic distances based on microsatellite markers are: 0.2321-1.2313. The study indicates that structural and microsatellite markers reflect the genetic variation of the three populations consistently: Tong>Hu>YRD. The differentiation between related species or interpopulations can be expressed more effectively by microsatellite markers than structural markers. Oar FCB11, MAF33, Oar AE101, Oar FCB128 and OarFCB304 can be used as representative loci for research on genetic differentiation between sheep and goat.


Structural Loci;Microsatellite Marker;Mean Heterozygosity;Standard Genetic Distance;Genetic Differentiation


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