The Effect of Lycii fructus beer intake on serum lipid profiles and antioxidant activity in rats

구기자 맥주의 섭취가 흰쥐의 혈청 지질패턴 및 항산화효소 활성에 미치는 영향

  • Chung, Hae-Kyung (Department of Food & Nutrition, College of Natural Science, Hoseo University) ;
  • Choi, Chang-Suk (Department of Food & Nutrition, College of Natural Science, Hoseo University) ;
  • Yang, Eun-Ju (Department of Culinary Science, Honam University) ;
  • Kang, Myung-Hwa (Department of Food & Nutrition, College of Natural Science, Hoseo University)
  • 정혜경 (호서대학교 자연과학대학 식품영양학과) ;
  • 최창숙 (호서대학교 자연과학대학 식품영양학과) ;
  • 양은주 (호남대학교 조리과학과) ;
  • 강명화 (호서대학교 자연과학대학 식품영양학과)
  • Published : 2004.02.28


This study was performed to investigate the effect of Lycii fructus beer on serum lipid profiles and antioxidant activity in rat Sprague-Dawley (SD) rats weighting about 190g were divided into the following 5 groups ; distillate water (Control), 5% ethanol in distillate water (Ethanol), commercial beer (CB), Lycii fructus beer (LFB) and 5% alcohol red wine diluted with distillate water (RW). Body weight, total food intake, FER and percent organ (liver, kidney) weight per body weight were not significantly changed by Lycii fructus beer drinking. After 6 weeks, serum total cholesterol, triglyceride and HDL cholesterol level were not significantly different. But, Lycii fructus beer intake tended to decrease serum triglyceride level and atherogenic index. Also, GOT and GPT levels were expressed lower than Ethanol group. There was not significantly different in hepatic glutatiione (GSH) content and glutathione-S-transferase (GST) activities among 5 groups. Lipid peroxidation in the hepatic was decreased by Lycii fructus beer intake. The results demonstrated that Lycii fructus beer was potential and effective antioxidant that can protect the decrease associated with alcohol.


Lycii fructus beer;atherogenic index;glutathione;glutathione-S-transferase


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