Intercalation of Vitamer into LDH and Their Controlled Release Properties

  • Choy, Jin-Ho (National Nanohybrid Materials Laboratory, School of Chemistry and Molecular Engineering, Seoul National University) ;
  • Son, You-Hwan (National Nanohybrid Materials Laboratory, School of Chemistry and Molecular Engineering, Seoul National University)
  • Published : 2004.01.20


Biofunctional nanohybrids are synthesized from layered double hydroxide (LDH) and the vitamins such as ascorbic acid and topopherol acid succinate. Either ion exchange or copricipitaion leads to successful intercalation of the vitamins into gallery space of LDH that offers a new route to safe preservation of bioactivity as well as controlled release. Intercalations of vitamins are clearly reflected on the increase in the basal spacing of ZnAl-(Nitrate) LDH from 8.5 ${\AA}$ to 10.5 ${AA}$ for ascorbate, and 49.0 ${AA}$ for tocopherol acid succinate, respectively. No significant change in UV-Vis and IR absorption characteristics of the intercalated vitamins strongly supports the safe maintenance of their bioactivities without any deterioration of chemical and structural integrity. Furthermore, it is shown that the hybridized vitamins could be discharged in a controlled kinetics.


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