Association of Genetic Polymorphisms of Estrogen Receptor with Litter Size using PCR-RFLP in Yorkshire Swine

Yorkshire종 돼지에서 PCR-RFLP을 이용한 Estrogen Receptor의 유전적 다형과 산자수간의 관련성

  • Kim, J.E. (Dept. of Animal Science Faculty of Agricultural Sciences university of British Columbia 2357 Main Mall, Vancouver, BC Canada V6T IZ4) ;
  • Song, W.C. (Division of Biotechnology and Genetic Enginnering, College of Life and Environmental Sciences Korea University) ;
  • Choi, B.D. (Division of Biotechnology and Genetic Enginnering, College of Life and Environmental Sciences Korea University) ;
  • Kho, Y. (Division of Biotechnology and Genetic Enginnering, College of Life and Environmental Sciences Korea University) ;
  • Park, S.S. (Graduate School of Biotechnology, Korea university) ;
  • Hong, K.C. (Division of Biotechnology and Genetic Enginnering, College of Life and Environmental Sciences Korea University)
  • 김지은 ;
  • 송원철 (고려대학교 생명환경과학대학 생명유전공학부) ;
  • 최봉도 (고려대학교 생명환경과학대학 생명유전공학부) ;
  • 고용 (고려대학교 생명환경과학대학 생명유전공학부) ;
  • 박성수 (고려대학교 생명공학원) ;
  • 홍기창 (고려대학교 생명환경과학대학 생명유전공학부)
  • Published : 2003.08.30


This study was performed to investigate a possible association of the porcine estrogen receptor(ER) locus with the total number of born(TNB) and number of born alive(NBA) in Yorkshire pigs. Using DNAs extracted from 242 Yorkshire pigs, the ER genotype was determined by PvuII PCR-RFLP. The ER allele frequencies of two types of A and B were 0.39 and 0.61, respectively. The least squares means of the litter size by ER genotype was evaluated. The TNB and NBA were found to be associated with an specific ER allele. The genotype at the porcine ER locus has an application potential for marker-assisted selection for litter size in pigs.


Estrogen receptor locus;RFLP;Litter size;Yorkshire pig


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