Evaluation of Recombinant Human Lactoferricin Culture as a Substitute for Antibiotic in Pig Starter Diets

이유자돈사료에 항생제를 대체하기 위한 재조합 인간 락토페리신 컬처의 평가

  • Hong, J.W. (Department of Animal Resource & Sciences, Dankook University) ;
  • Kim, I.H. (Department of Animal Resource & Sciences, Dankook University) ;
  • Hwang, I.H. (Easy-Bio System, Inc.) ;
  • Lee, J.H. (Easy-Bio System, Inc.) ;
  • Kim, J.H. (Agribrands Purina Korea, Inc.) ;
  • Kwon, O.S. ;
  • Lee, S.H. (Department of Animal Resource & Sciences, Dankook University)
  • 홍종욱 (단국대학교 동물자원과학과) ;
  • 김인호 (단국대학교 동물자원과학과) ;
  • 황일환 ((주)이지바이오시스템) ;
  • 이지훈 ((주)이지바이오시스템) ;
  • 김지훈 ((주)애그리브랜드 퓨리나 코리아) ;
  • 권오석 (단국대학교 동물자원과학과) ;
  • 이상환 (단국대학교 동물자원과학과)
  • Published : 2003.08.30


Sixty [(Duroc${\times}$Yorkshire)${\times}$Landrace] pigs (7.63$\pm$0.41kg average body weight and 25-d average age) were used in a 20-d growth assay to determine the effect of dietary recombinant human lactoferricin culture (RHLC) supplementation on growth performance, digestibility and plasma IgG concentration in weaning pigs. Dietary treatments included 1) Negative control (NC : without antibiotic), 2) Positive control (PC : NC diet + 0.1% chlortetracycline), 3) RHLC0.3 (NC diet + 0.3% RHLC), 4) RHLC0.5 (NC diet + 0.5% RHLC). No differences were found among treatments in average daily gain (P>0.05). ADFI of pigs fed RHLC0.3 diet was higher than that of pigs fed PC diet (P<0.05). However, pigs fed RHLC0.5 diet had improved gain/feed compared to pigs fed PC diet. Pigs fed PC and RHLC diets showed significantly increased dry matter digestibility compared to pigs fed NC diet (P<0.05). There was no significant difference in plasma IgG concentrations (P>0.05). The supplementation of RHLC in starter pig diets appears to be an alternative to antibiotics.


Recombinant human lactoferricin culture;Antibiotic-free diet;Pigs


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