Uncertainty evaluation of dioxin analysis in blood samples

혈액 시료 중 다이옥신의 농도 분석 결과에 대한 불확도 평가

  • Mun, Su-Jung (School of Environmental Science and Engineering, Pohang University of Science and Technology) ;
  • Kim, Byung-Hoon (School of Environmental Science and Engineering, Pohang University of Science and Technology) ;
  • Woo, Jin-Chun (Inorganic Analytical Chemistry Group, Korea Research Institute of Standards and Science) ;
  • Chang, Yoon-Seok (School of Environmental Science and Engineering, Pohang University of Science and Technology)
  • 문수정 (포항공과대학교 환경공학부) ;
  • 김병훈 (포항공과대학교 환경공학부) ;
  • 우진춘 (한국표준과학연구원 무기분석그룹) ;
  • 장윤석 (포항공과대학교 환경공학부)
  • Received : 2003.06.07
  • Accepted : 2003.10.30
  • Published : 2003.12.25

Abstract

Uncertainty of final measurement results considering main uncertainty sources being in dioxin analysis of a blood sample was estimated. 'The Guide to the Expression of Uncertainty in Measurement' was suggested for accomplishment of this study. After uncertainties for the 11 compounds detected in this experiment of the 17 target compounds of dioxin and furan were calculated considering the uncertainty sources of each step, uncertainty for the total dioxin concentration was estimated by combining these values. The concentration of dioxin in blood sample was expressed as $0.0746{\pm}0.0074pg$ I-TEQ/g weight or $20.68{\pm}2.04pg$ I-TEQ/g lipid, including the uncertainty values obtained in this way. The former expression indicates the conversion concentration into the sample weight and the latter one indicates the conversion concentration into the lipid weight. The quality of measured analytical results could be assured quantitatively by estimating uncertainty of measurement results and showing the range of measurand.

Keywords

Acknowledgement

Supported by : 환경부, 한국학술 진흥재단

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