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Relationships of Plasma Insulin-like Growth Factor (IGF)-I and IGF-II Concentrations to Litter Size

Landrace와 Yorkshire 돼지에서 혈장의 Insulin-like Growth Factor (IGF)-I과 IGF-II 농도와 산자수 및 비유성적과의 관계

  • Lee, C. Y. (Regional Animal Industry Research Center, Jinju National University) ;
  • Baik, K. H. (Regional Animal Industry Research Center, Jinju National University) ;
  • Lee, D. H. (Department of Life Science, University of Seoul) ;
  • Park, H. C. (Swine Breeding Center of National Agricultural Cooperatives Federation)
  • 이철영 (진주산업대학교 동물생명산업 지역협력연구센터) ;
  • 백규흠 (진주산업대학교 동물생명산업 지역협력연구센터) ;
  • 이동희 (서울시립대학교 생명과학과) ;
  • 박화춘 (농협중앙회 종돈사업소)
  • Published : 2003.02.28

Abstract

The present study was undertaken to find relationships of plasma insulin-like growth factor (IGF)-I and IGF-II concentrations to litter size and lactation performance. Sixty pure-bred Landrace and Yorkshire pigs having similar farrowing weeks which had been selected from a large number of pregnant gilts and sows were divided into low- (<${\mu}$-0.5SD) and high-litter size (>${\mu}$+0.5 SD) lines under a 2 (breed)${\times}$2 (line) factorial arrange of treatments. After adjusting the litter size to nine piglets per sow at farrowing, total litter weight was measured at three weeks postpartum at weaning as an index of milk yield. Blood samples were obtained from the jugular vein at day (d)-90 pregnancy (Px) and at d-15 postpartum. The litter size or the number of piglets born during the present experiment and the average litter size during the entire parities up to the present one were greater in the high-line than in the low-line by 3.7 and 2.4 piglets, respectively (P<0.01); effect of the breed on litter size was not significant. Plasma IGF-II concentration at d-90 Px was greater in the high-line than in the low-line. Litter size and d-90 Px IGF-I concentration were negatively correlated in Landrace (r=-0.46; P<0.05) and tended to be negatively correlated in Yorkshire (r=-0.31; P=0.09), which resulted in a significant negative correlation between these two variables in total animals (r=-0.35; P<0.01). Litter weight at weaning was not different between the two breeds or lines. Relationships between the litter weight and IGF concentration were not consistent across the breed ${\times}$ physiological stage combinations. Results suggest that d-90 Px IGF concentrations may be indicative of the litter size at impending farrowing.

Keywords

IGF;Litter;Pregnancy;Lactation;Pig

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