A Medicinal Herbal Tea Increases Success Rate and Reduces Withdraw Symptoms of Smoking Cessation in Men

  • Lee, Ho-Jae (Department of Food Science and Biotechnology, Dong-eui Institute of Technology) ;
  • Hur, Sung-Ho (Department of Food Science and Biotechnology, Dong-eui Institute of Technology) ;
  • Hur, Min-Soo (Department of Food Science and Technology/Institute of Seafood Science, Pukyoung National University) ;
  • Lee, Yang-Bong (Department of Food Science and Technology/Institute of Seafood Science, Pukyoung National University)
  • Published : 2003.12.01


The efficacy of a medicinal herb tea (MHT) for assisting smoking cessation and for reducing withdrawal symptoms was evaluated by a placebo controlled subjective test in 100 male smokers. The MHT group experienced less craving for the taste of tobacco, and was more successful at quitting smoking. Among the subjects continuing to the final stage, 23 subjects (38.3 %) who took the MHT and 2 subjects (10.0 %) who took the placebo tea succeeded in quitting smoking. In the group taking MHT, urinary cotinine concentration increased during the first 2 weeks and then greatly decreased from weeks 2 to 4. The urinary cotinine concentration in the MHT group at week 0 was 38.6 mol/L but decreased to 24.5 mol/L by the end of week 4. MHT also reduced withdrawal symptoms, a frequent reason for failure in reducing or quitting smoking. The effects of the herbal tea on smoking cessation and withdrawal symptoms may be attributed to increased metabolism of nicotine and other effects of unidentified components of the herbal ingredients.


  1. Toxicology v.166 Smoking cessation in cancer prevention Vainio H;Weiderpass E;Kleihues P
  2. J Nat'l Cancer Inst v.91 Tobacco smoke carcinogens and lung cancer Hecht SS
  3. Hypertension v.39 Cardiovascular effects of nasal and transdermal nicotine and cigarette smoking Benowitz NL;Hansson A;Jacob P III
  4. Hypertension v.37 Effects of smoking cessation on changes in blood pressure and incidence of hypertension Lee DH;Ha MH;Kim JR; Jacobs DR Jr
  5. New Jersey Medicine v.85 Smoking cessation in primary care settings Orleans CT
  6. Psychiatry v.31 Depression and depressive symptoms in smoking cessation comprehensive Covey LS;Glassman AH;Stetner F
  7. Diagnostic and statistical manual of mental disorders APA
  8. Brain Res v.850 Nicotine abstinence in the mouse Isola R;Vogelsberg V;Wemlinger TA;Neff NH;Hadjiconstantinou M
  9. Biological Psychiatry v.49 Overview of nicotini receptors and their roles in the central nervous system Dani JA
  10. Behavioural Brain Research v.113 The putative role of extra-synaptic mesolimbic dopamine in the neurobiology Balfour DJ;Wright AE;Benwell ME;Birrell CE
  11. Eur J Pharmacol v.393 Role of dopamine in the behavioral actions of nicotine related to addiction Di Chiara G
  12. J Neurobiol v.53 Cellular and synaptic mechanisms of nicotine addiction Mansvelder HD;McGehee DS
  13. Trends in Pharmacological Sciences v.23 Nicotine addition:the possible role of functional upregulation Buission B;Bertrand D
  14. Addiction v.98 Smoking reduction promotes smoking cessation:results from a double blind, randomized, placebo-controlled trial of nicotine gum with 2-year follow-up Wennike P;DanielssonT;Landfeldt B;Westin A;Tonnesen P
  15. Psychopharmacology v.164 Smokers deprived of cigaretts for 72 h: effect of nicotine patches on craving and withdrawal Teneggi V;Tiffany ST;Squassante L;Milleri S;Ziviani L;Bye A
  16. Int J Tuberc Lung Dis v.7 Role of nicotine pharmacokinetics in nicotine addiction and nicotine replacement therapy: a review Le Houezec J
  17. Drugs v.62 Clinical efficacy of Bupropion in the management of smoking cessation Jorenby D
  18. Biochem Pharmacol v.63 A novel mechanism of action and potential use for lobeline as a treatment for psychostimulant abuse Dwoskin LP;Crooks PA
  19. J Food Sci Nutr v.8 Antioxidant and nicotine degradation effects of medicinal herbs Lee HJ;Hur SH;Shin EC;Lee YB
  20. J Chromatography v.419 Simultaneous determination of nicotine, cotinine and five additional nicotine metabolites in the urine of smokers using pre-column derivatization and high-performance liquid chromatography Barlow RD;Thompson PA;Stone RB
  21. British J Addiction v.86 The Fagerstrom test for nicotine dependence: a revision of the Fagerstrom Heatherton TF;Kozlowski LT;Frecker RC;Fagerstrom KO
  22. Psychopharmacology (Berl) v.50 Smoking withdrawal symptoms in two weeks of abstinence Shiffman SM;Jarvik ME
  23. Pharmacol Biochem Behav v.72 Modulation of mood and cognitive performance following acute administration of Melissa officinalis (lemon balm) Kennedy DO;Scholey AB;Tildesley NT;Perry EK;Wesnes KA