Pine Needle Oil and Korean Medicinal Herb Complex Protect Hyperlipidemia and Liver Cell Damage Induced by Alcohol

  • Park, Kap-Joo (Department of Biological Sciences, Konkuk University) ;
  • Kim, Kang-Sung (Department of Food Science and Nutrition, Yongin University) ;
  • Ahn, Ki-Heung (Department of Biological Sciences, Konkuk University) ;
  • Rhee, Joon-Shick (Department of Biological Sciences, Korea Advanced Institute of Science and Technology)
  • Published : 2003.12.01


The effect of treatment with pine needle oil complex (complex of pine needle oil and Korean medicinal herbs) upon rat hepatocytes exposed to alcohol was investigated. We compared body weight gain and ratios of liver and kidney to body weight and the serum biochemistry of rats administered both alcohol and Pine needle oil complex to control rats treated with alcohol alone. Pine needle oil complex treatment resulted in a significant reduction in the levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT) and triglycerides (TG) compared to the control rats. These data suggest that Pine needle oil complex represents an excellent candidate for protection of rat hepatocytes from alcohol-mediated damage.


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