Effect of Neuronal Differentiation Activity of Hot Water Extracts of Marine Alga, Chlorella capsulata

해수 미세조류인 Chlorella capsulata의 열 수 추출물의 신경세포 분화촉진에 관한 연구

  • 이현용 (강원대학교 바이오 산업공학부) ;
  • 이현수 (강원대학교 바이오 산업공학부) ;
  • 이서호 (강원대학교 바이오 산업공학부) ;
  • 김대호 (강원대학교 바이오 산업공학부) ;
  • 박진홍 (강원대학교 바이오 산업공학부)
  • Published : 2003.06.01

Abstract

Hot water extracts of Chlorella capsulata(CCE) is a biological response modifier (BRM) which exhibits neuronal differentiation activity. The effect of CCE on the growth of nerve cells, PC12 was observed as follows: The viable cell density in adding CCE was increased up to 2.5 times, compare to that in no addition. The neurite of the cells was also lengthened up to 40 $\mu\textrm{m}$ longer than 5 $\mu\textrm{m}$ in no addition. The number of neurite-bearing cells were about four times higher than that in no addition.

Keywords

Marine alga;Chlorella capsulata;neuronal differentiation activity;PC12 nerve cell.

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