DOI QR코드

DOI QR Code

Association among Egg Productivity, Granulosa Layer IGF-I, and Ovarian IGF-I in Korean Native Ogol Chicken

  • Kang, W.J. ;
  • Seo, D.S. ;
  • Ko, Y.
  • Received : 2002.08.02
  • Accepted : 2002.12.20
  • Published : 2003.03.01

Abstract

There exists considerable evidence that insulin-like growth factor-I (IGF-I) is involved in the regulation of ovulation rate and follicle development. IGF-I is believed to modulate the effects of gonadotropins on follicular growth and cell differentiation via paracrine and autocrine mechanisms. Therefore, this study was performed to relate the expression of IGF-I on ovaries and follicles with egg productivity at 60 wk. The egg productivity of 70 KNOC was recorded from 20 to 60 wk. Blood was taken every 10 wk and ovaries and follicles were taken at 60 wk. Serum IGF-I and IGF-I of ovaries and follicles were measured by radioimmunoassay. Based on egg production levels up to 60 wk and ovarian IGF-I expression at 60 wk, respectively. Chickens were divided into two groups, high and low. Egg production and serum IGF-I in the high IGF-I group were higher than those in the low group. Moreover, the IGF-I expression of follicles in the high ovarian IGF-I expression group was higher than that in the low group. These finding are consistent with the report that IGF-I indirectly regulates ovulation in chickens, suggesting that this regulation may play an important role in improved egg productivity.

Keywords

IGF-I;Egg productivity;Ovary;Follicle;KNOC

References

  1. Adashi, E. Y., C. E. Resnick, A. Hurwitz, E. Ricciarelli, E. R. Hernandez, C. T. Roberts, Jr., D. LeRoith and R. G. Rosenfeld. 1992. The intra-ovarian IGF system. Growth Regul. 2:10-15.
  2. Armstrong, D. G. and C. Hogg. 1996. Insulin-like growth factor-I (IGF-I), II and type-I IGF receptor gene expression in the ovary of the laying hen. J. Reprod. Fertil. 106:101-6.
  3. Kang, W. J., J. S. Yun, D. S. Seo, K. C. Hong and Y. Ko. 2001. Relationship among egg productivity, steroid hormones (progesterone and estradiol) and ovary in Korean Native Ogol Chicken. 14:922-928.
  4. McMurtry, J. P. 1998. Nutritional and developmental roles of insulin-like growth factors in poultry. J. Nutr. 128:302S-5S. https://doi.org/10.1093/jn/128.2.302S
  5. Mondschein, J. S., S. F. Canning, D. Q. Miller and J. M. Hammond. 1989. Insulin-like growth factors (IGFs) as autocrine/paracrine regulators of granulosa cell differentiation and growth: studies with a neutralizing monoclonal antibody to IGF-I. Biol. Reproduction. 41:79-85.
  6. SAS. 1995. SAS/STAT Software for PC. Release 6.11, SAS institute, Cary, NC. U.S.A
  7. Su. H. and F. G. Silversides. 1996. Effects of sex-linked imperfect albinism (Sal-s) in the chicken on the relationships of plasma concentrations of progesterone and $17{\beta}$-estradiol with egg production. Poult. Sci. 75:13-9. https://doi.org/10.3382/ps.0750013
  8. Onagbesan, O. M., E. Decuypere, F. Leenstra and D. A. Ehlhart. 1999a. Differential effects of feeding level on cell proliferation and progesterone production in response to gonadotrophins and insulin-like growth factor-I by ovarian granulosa cells of broiler breeder chicken selected for growth (GL) and food conversion (FC). J. Reprod. Fertil. 118:73-85.
  9. Onagbesan, O. M., B. Vleugels, N. Buys, V. Bruggeman, M. Safi and E. Decuyoere. 1999b. Insulin-like growth factors in the regulation of avian ovarian functions. Domestic Anim. Endocrinol. 17:299-313. https://doi.org/10.1016/S0739-7240(99)00046-6
  10. Robert, J. Etches. 1996. Reproduction in Poultry, CAB International, pp. 1-9.
  11. Whitehead, C. C., A. S. Bowman and H. D. Griffin. 1993. Regulation of plasma oestrogen by dietary fats in the laying hen: relationships with egg weight. Br. Poult. Sci. 34:999-1010. https://doi.org/10.1080/00071669308417659
  12. Kang, W. J., J. S. Yun, D. S. Seo, C. Y. Lee, K. C. Hong and Y. Ko. 2000. Study on the association between early egg productivity and serum insulin-like growth factor-I in Korean Native Ogol Chicken. J. Anim. Sci. Technol. (Korea). 42:767-776.
  13. Humbel, R. E. 1990. Insulin-like growth factors I and II. Eur. J. Biochem. 190:445-462.
  14. McMurtry, J. P., G. L. Francis and Z. Upton. 1997. Insulin-like growth factors in poultry. Domest. Anim. Endocrinol. 14:199-299. https://doi.org/10.1016/S0739-7240(97)00019-2
  15. Daughday, W. H., I. K. Mariz and S. L. Blethen. 1980. Inhibition of access of bound somatomedin to membrane receptor and immunobinding sites: a comparison of radioreceptor and radioimmunoassays of somatomedin in native and acidethanol-extracted serum. J. Clin. Endocrinol. Metab. 51:781-788. https://doi.org/10.1210/jcem-51-4-781
  16. Guidice, L. C. 1992. Insulin-like growth factors and ovarian follicular development. Endocrine Rev. 13:641-69.
  17. Roberts, R. D., P. J. Sharp, D. W. Burt and C. Goddard. 1994. Insulin-like growth factor-I in the ovary of laying hen: gene expression and biological actions on granulosa and theca cells. Gen. Comp. Endocrinol. 93:327-36. https://doi.org/10.1006/gcen.1994.1037
  18. Spicer, L. J. and S. E. Echternkamp. 1995. The ovarian insulin and insulin-like growth factor system with emphasis on domestic animals. Domest. Anim. Endocrinol. 12:223-45. https://doi.org/10.1016/0739-7240(95)00021-6
  19. Bergh, C., B. Carlsson, J. Olsson, U. Selleskog and T. Hillensjo. 1993. Regulation of androgen production in cultured human thecal cells by insulin-like growth factor-I and insulin-like growth system with emphasis on domestic animals. Domest. Anim. Endocrinol. 12:223-45. https://doi.org/10.1016/0739-7240(95)00021-6
  20. Etches, R. J. 1990. The ovulatory cycle of the hen. Curr. Rev. Poult. Biol. 2:293-318.
  21. Spencer, G. S., E. Decuypere, J. Buyse and M. Zemen. 1996. Effects of recombinant human insulin-like growth factor-II on weight gain and body composition of broilor chickens. Poult. Sci. 75:388-92. https://doi.org/10.3382/ps.0750388
  22. Ballard, F. J., R. J. Johnson, P. C. Owens, G. L. Francis, F. M. Upton, J. P. McMurtry and J. C. Wallace. 1990. Chicken insulin-like growth factor-I; Amino acid sequence, radioimmunoassay and plasma levels between strains and during growth. Gen. Comp. Endocrinol. 79:459-68. https://doi.org/10.1016/0016-6480(90)90076-X
  23. Lee, C. Y. and D. M. Henricks. 1990. Comparisons of various acidic treatments of bovine serum on insulin-like growth factor-I immunoreactivity and binding activity. J. Endocrinol. 127:139-148. https://doi.org/10.1677/joe.0.1270139
  24. Ohh, B. K. 1988. Poultry Science. Moonundang Company, Seoul, Korea. (In Korean).

Acknowledgement

Supported by : Research Program of the Ministry of Agriculture and Forestry