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Mapping Quantitative Trait Loci for Meat Quality on Pig Chromosome 3, 4 and 7

  • Zuo, Bo ;
  • Xiong, YuanZhu ;
  • Su, YuHong ;
  • Deng, ChangYan ;
  • Zheng, Rong ;
  • Jiang, Siwen
  • Received : 2002.07.02
  • Accepted : 2002.11.04
  • Published : 2003.03.01

Abstract

The objective of this study was to localize QTL affecting meat quality in a pig family of three generations. All animals were genotyped for twenty-four microsatellites on SSC3 (Sus scrofa chromosome 3), SSC4 and SSC7. One hundred and forty $F_2$ offsprings were scored for eleven meat quality traits. Least square regression interval mapping revealed quantitative trait loci (QTL) effect for meat pH (m. Semipinalis Capitis, SC) on SSC4 and SSC7; for moisture (m. Longissimus Dorsi, LD) on SSC3. Furthermore, there was suggestive evidence for a QTL on SSC4 affecting intramuscular fat (IMF) content that nearly approached the chromosomewise (p=0.05) significance threshold.

Keywords

Genome Scan;Quantitative Trait Loci (QTL);Meat Quality;Pigs

References

  1. Andersson-Eklund, L., L. Marklund, K. Lundstrom, C. S. Haley, K. Andersson, I. Hansson, M. Moller and L. Andersson. 1998. Mapping quantitative trait loci for carcass and meat traits in a Wild boar${\times}$Large White intercross. J. Anim. Sci. 76:694-700 https://doi.org/10.2527/1998.763694x
  2. De Koning, D. J., B. Harlizius, A. P. Rattink, J. A. M. van Arendonk and E. W. Brascamp. 2000a. Detection and characterization of quantitative trait loci for carcass and meat quality traits in pigs. Proc. Eur. Assoc. Anim. Prod. 6, 3
  3. Haley, C. S., S. A. Knott and J. M. Elsen. 1994. Mapping quantitative trait loci in cross between outbred lines using least square. Genetics 136:1195-1207.
  4. Marklund, L., A. K. Wintero, P. D. Thomsen, M. Johansson, M. Fredholm, U. Gustafsson and L. A. Andersson. 1993. Linkage group on pig chromosome 4 comprising the loci for blood group L, GBA, ATP1B1 and three microsatellites. Anim. Genet. 24:333-338. https://doi.org/10.1111/j.1365-2052.1993.tb00336.x
  5. Marklund, L., M. Johansson-Moller, B. Hoyheim, W. Davis, M. Fredholm, R. K. Juneja, P. Marinai, W. Coppierters, H. Ellegren and L. Andersson. 1996. A comphrensive linakage map of the pig based on a wild pig -large white intercross. Anim. Genet. 27:225-269.
  6. Milan, D., J. P. Bidanal, P. Le Roy, C. Chevalet, N. Woloszyn, J. C. Caritez, J. Gruand, H. Lagant, M. B. Lefaucheur, C. Renard, M. Vaiman, P. Mormede, C. Desautes, Y. Amigues, F. Bourgeois, J. Gellin and L. Ollivier. 1998. Current status of QTL detection in Large White${\times}$Meishan crosses in France. Proceedings of the 6th World Congress on Genetics Applied to Livestock Production. 26:414-417.
  7. Rattink, A. P., D. J. De Koning, M. Faivre, B. Harlizius, J. A. M. van Arendonk and M. A. M. Groenen. 2000. Fine mapping and imprinting analysis for fatness trait QTLs in pigs. Mamm. Genome. 11:656-661.
  8. Robic, A., J. Riquet, M. Yerle, D. Milan, Y. Lahbib-Mansais, C. Dubut-Fontana and J. Gellin. 1996. Porcine linkage and cytogenetic maps intergrated by regional mapping of 100 microsatellites on somatic cell hybrid panel. Mamm. Genome. 7:438-445. https://doi.org/10.1007/s003359900129
  9. Wang, L., T. P. Yu, C. K. Tuggle, H. C. Liu and M. F. Rothschild. 1998. A directed search for quantitative trait loci on chromosome 4 and 7 in the pig. J. Anim. Sci. 76:2560-2567. https://doi.org/10.2527/1998.76102560x
  10. Xiong, Y. Z. and C. Y. Deng. 1999. Principle and method of swine testing. Chinese Agricultural Press, Beijing.
  11. Zuo, B., Y. Z. Xiong, Y. H. Su, C. Y. Deng, R. Zheng, M. G. Lei and L. Yu. 2003. Mapping and genetic effect analysis of swine quantitative trait loci using 24 microsatellites. Acta Veterinaria et Zootechnica Sinica (China). In press.
  12. Malek, M., J. C. M. Dekkers, H. K. Lee, T. J. Bass and M. F. Rothchild. 2001. A molecular genome scan analysis to identify chromosomal regions influencing economic traits in the pig. Ⅱ: Meat and muscle composition. Mamm. Genome. 12:637-645. https://doi.org/10.1007/s003350020019
  13. Gerbens, F., A. Jansen, A. J. M. Van Erp, F. L. Harders and T. H. E. Meuwissen, G. Rettenberger, J. H. Veerkamp and M. F. W. Tepas. 1998. The adipocyte fatty acid-binding protein locus: characterization and association with intramuscular fat content in pigs. Mamm. Genome. 9:1022-1026. https://doi.org/10.1007/s003359900918
  14. Green, P., K. Falls and S. Crooks. 1990. Document for CRIMAP, wersion 2.4. Washington Uni. School of Medicine. St. Louis, MO.
  15. Gerbens, F., D. J. de Koning, F. L. Harders, T. H. E. Meuwissen, L. L. G. Janss, M. A. M. Groenen, J. H. Veerkamp, J. A. M. Van Arendonk and M. F. W. Tepas. 2000. The effect of adipocyte fatty acid-binding protein genes on intramuscular fat and backfat content in Meishan crossbred pigs. J. Anim. Sci. 78:552-559. https://doi.org/10.2527/2000.783552x
  16. De Koning, D. J., A. P. Rattink, B. Harlizius, J. A. M. van Arendonk and E. W. Brascamp. 2000b. Genome-wide scan for body composition in pigs reveals important role of imprinting. Proc. Natl. Acad. Sci. USA. 97:7947-7950. https://doi.org/10.1073/pnas.140216397
  17. De Koning, D. J., L. L. G. Janss, A. P. Rattink, P. A. M. Van Oers, B. J. De Vries, M. A. M. Groenen, J. J. van der Poel, P. N. de Groot, E. W. Brascamp and J. A. M. van Arendonk. 1999. Detection of quantitative trait loci for backfat thickness and intramuscular fat content in pigs. Genetics 152:1679-1690.
  18. Ovilo, C., M. Perez-Enciso, C. Barragan, A. Clop, C. Rodriguez, M. A. Oliver, M. A. Toro and J. L. Noguera. 2000. A QTL for intramuscular fat and backfat thickness is located on porcine chromosome 6. Mamm. Genome. 11:344-340. https://doi.org/10.1007/s003350010065
  19. Moser, G., E. Mueller, P. Beckmann, G. Yue and H. Geldermenn. 1998. Mapping of QTLs in F2 generations of Wild Boar, Pietrain and Meishan pig. Proceeding of the 6th World Congress on Genetics Applied to Livestock Production. 26: 478-481.
  20. Wu, X. L., C. Lee, J. Jiang, Y. L. Peng, S. L. Yang, B. N. Xiao, X. C. Liu and Q. S. Shi. 2001. Mapping a quantitative trait locus for growth and backfat on porcine chromosome 18. Asian-Aust. J. Anim. Sci. 14:1665-1669.
  21. Wu, X. L., C. Lee, J. Jiang, Y. L. Peng, H. F. Yan, S. L. Yang, B. N. Xiao, X. C. Liu and Q. S. Shi. 2002. Quantitative trait loci mapping for porcine backfat thickness. Asian-Aust. J. Anim. Sci. 15:932-937.
  22. Meuwissen, T. H. E. and M. E. Goddard. 1996. The use of marker haplotypes in animal breeding schemes. Genet. Sel. Evol. 28(2):161-176. https://doi.org/10.1186/1297-9686-28-2-161
  23. Webb, A. J. 1998. Objective and strategies in pig improment and applied perspective. J. Dairy Sci. 81(Suppl. 2):36-46. https://doi.org/10.3168/jds.S0022-0302(98)70152-3

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