Association of a Single Nucleotide Polymorphism in the 5'-Flanking Region of Porcine HSP70.2 with Backfat Thickness in Duroc Breed

  • Chen, Ming-Yu (Department of Life Science, National Tsin-Hua University) ;
  • Huang, San-Yuan (Division of Biotechnology, Animal Technology Institute Taiwan) ;
  • Lin, En-Chung (Division of Applied Biology, Animal Technology Institute Taiwan) ;
  • Hseu, Tzong-Hsiung (Department of Life Science, National Tsin-Hua University) ;
  • Lee, Wen-Chuan (Division of Biotechnology, Animal Technology Institute Taiwan)
  • Received : 2002.06.11
  • Accepted : 2002.09.10
  • Published : 2003.01.01


Higher environmental temperature affects the economic performance of pigs. Heat shock protein 70 has been shown to play an important role in thermoresistance. The purpose of this study was to assess the effect of a single nucleotide polymorphism in the 5'-flanking region of porcine HSP70.2 on growth performance in Taiwanese Duroc. The genotype of this nt 393 polymorphic site could be verified by digestion with Bsa WI restriction enzyme of a PCR product. Pigs with TT and TC genotypes have thinner backfats than those with CC type (p<0.05). The result suggested that the polymorphic Bsa WI site in the 5'flanking region of porcine HSP70.2 may be used as a marker for the early selection of ultrasonic backfat thickness in Duroc pigs.


Pigs Duroc;Heat Shock Protein 70;Growth Performance;Polymorphism


Supported by : Council of Agriculture


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