- Volume 16 Issue 4
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Increase in Plasma HDL-Cholesterol Concentration in Goats Fed Sesame Meal Is Related to Ether Extract Fraction Included in the Meal
- Hirano, Y. (Laboratory of Glassland Science, University Farm, Graduate School of Bioagricultural Sciences, Nagoya University) ;
- Yokota, H. (Laboratory of Glassland Science, University Farm, Graduate School of Bioagricultural Sciences, Nagoya University) ;
- Kita, K. (Laboratory of Glassland Science, University Farm, Graduate School of Bioagricultural Sciences, Nagoya University)
- Received : 2002.07.23
- Accepted : 2002.11.21
- Published : 2003.04.01
Previously, we reported that a diet including sesame meal (SM) increased plasma total and high-density lipoprotein (HDL)-cholesterol concentrations in goats. In the present study, the components in the sesame meal that can increase plasma total and HDL-cholesterol concentrations have been examined. In experiment 1, we gave goats defatted sesame meal diet (DSM) to investigate the influence of ether extract fraction remained in sesame meal. Corn gluten meal diet (CGM) was also fed to goats as a high-protein diet to examine the influence of high dietary protein level caused by usage of sesame meal. Plasma total and HDL-cholesterol concentrations of goats fed DSM and CGM did not change during experimental periods though they were elevated by feeding SM. In experiment 2, the influence of sesame oil and corn oil added in diets on plasma total and HDL-cholesterol concentrations in goats was investigated. Plasma total and HDL-cholesterol concentrations were increased by feeding both corn oil diet and sesame oil diet. In conclusion, the increase in plasma HDL-cholesterol concentration by feeding sesame meal was resulted by the effect of ether extract fraction including sesame oil or some lipid-soluble components remained in sesame meal.
- Beynen, A. C., J. Th. Schonewille and A. H. M. Terpstra. 2000. Influence of amount and type of dietary fat on plasma cholesterol concentrations in goats. Small Ruminant Res. 35:141-147. https://doi.org/10.1016/S0921-4488(99)00089-9
- Hirano, Y., T. Kashima, N. Inagaki, K. Uesaka, H. Yokota and K. Kita. 2002. Dietary sesame meal increase plasma HDLcholesterol concentration in goats. Asian-Aust. J. Anim. Sci. 15:1564-1567. https://doi.org/10.5713/ajas.2002.1564
- Hirata, F., K. Fujita, Y. Ishikura, K. Hosoda, T. Ishikawa and H. Nakamura. 1996. Hypocholesterolemic effect of sesame lignan in humans. Atherosclerosis. 122:135-136. https://doi.org/10.1016/0021-9150(95)05769-2
- Hirose, N., T. Inoue, K. Nishihara, M. Sugano, K. Akimoto, S. Shimizu and H. Yamada. 1991. Inhibition of cholesterol absorption and synthesis in rats by sesamin. J. Lipid Res. 32:629-638.
- Kang, M. H., M. Naito, K. Sakai, K. Uchida and T. Osawa. 2000. Mode of action of sesame lignans in protecting low-density lipoprotein against oxidative damage in vitro. Life Sci. 66:161-171. https://doi.org/10.1016/S0024-3205(99)00574-3
- Kang, M. H., Y. Kawai, M. Naito and T. Osawa. 1999. Dietary defatted sesame flour decreases susceptibility to oxidative stress in hypercholesterolemic rabbits. J. Nutr. 129:1885-1890.
- Kang, M. H., M. Naito, N. Tsujihara and T. Osawa. 1998. Sesamolin inhibits lipid peroxidation in rat liver and kidney. J. Nutr. 128:1018-1022.
- National Research Council. 1981. Nutrient Requirements of Goats. National Academy Press, Washington, DC, USA.
- Park, C. S. and W. Rafalowski. 1983. Effect of fat supplement on lipid metabolism of Holstein heifers. J. Dairy Sci. 66:528-534. https://doi.org/10.3168/jds.S0022-0302(83)81821-9
- Park, C. S. 1985. Influence of dietary protein on blood cholesterol and related metabolites of growing calves. J. Anim. Sci. 61:924-930. https://doi.org/10.2527/jas1985.614924x
- Satchithanandam, S., M. Reicks, R. J. Calvert, M. M. Cassidy and D. Kritchevsky. 1993. Coconut oil and sesame oil affect lymphatic absorption of cholesterol and fatty acids in rats. J. Nutr. 123:1852-1858.
Yamashita, K., Y. Iizuka, T. Imai and M. Namiki. 1995. Sesame seed and its lignans produce marked enhancement on vitamin E activity in rats fed a low
$\alpha$-tocopherol diet. Lipids 30:1019-1028. https://doi.org/10.1007/BF02536287
Yamashita, K., Y. Nohara, K. Katayama and M. Namiki. 1992. Sesame seed lignans and
$\gamma$-tocopherol act synergistically to produce vitamin E activity in rats. J. Nutr. 122:2440-2446. https://doi.org/10.1093/jn/122.12.2440