The Effect of Willow Leaf Extracts on Human Leukemic Cells in Vitro

  • El-Shemy, Hany A. (Department of Biochemistry, Faculty of Agriculture, Cairo University) ;
  • Aboul-Enein, Ahmed M. (Department of Biochemistry, Faculty of Agriculture, Cairo University) ;
  • Aboul-Enein, Mostafa I. (Department of Clinical Pathology, National Cancer Institute, Cairo University) ;
  • Issa, Sohair I. (Department of Clinical Pathology, National Cancer Institute, Cairo University) ;
  • Fujita, Kounosuke (Faculty of Applied Biological Science, Hiroshima University)
  • Received : 2003.01.05
  • Accepted : 2003.02.25
  • Published : 2003.07.31


The young developing leaves of willow (Salix safsaf, Salicaceae) trees have antileukemic activity. After a 24-h incubation in vitro, the crude water extracts of the leaves killed a majority of the blasts of acute myeloid leukemia (AML, 73.8%).


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