A Study on Growth Inhibition of Escherichia coli and Salmonella typhimurium by Lactic Acid Bacteria

유산균에 의한 Escherichia coli와 Salmonella typhimurium의 생육억제에 관한 연구

  • Kim, E.A. (Institute of Dairy Food Research, Seoul Dairy Cooperative) ;
  • Baick, S.C. (Institute of Dairy Food Research, Seoul Dairy Cooperative) ;
  • Chung, W.H. (Institute of Dairy Food Research, Seoul Dairy Cooperative)
  • Published : 2002.08.31


The inhibitory effect of lactobacilli and bifidobacteria on the growth of typical intestinal pathogens, Escherichia coli and Salmonella typhimurium was studied. The degree of inhibition was measured by well disc assay and turbidimetry method. The strains which showed the higher antimicrobial activity were L. acidophilus La-5, L. acidophilus NCFM, L. casei Lc-01 on the average by using two different methods. The associative cultures were performed with selected 3 lactobacilli and 2 enteropathogens E. coli and S. typhimurium, respectively. Inhibition of pathogen began at 9hr after culturing so that viable counts was decreased rapidly. After 30hr incubation, there were no viable pathogens from the mixed culture. Under this experimental condition, the antimicrobial activity of lactic acid bacteria was not due to pH alone and supposed to different to the strains.


Lactobacilli;Bifidobacteria;Antimicrobial activity;Associative culture


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