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The Effects of Mercury and Cadmium Administered in Subcutaneous Tissue on Enzymatic Activity and lipidperoxidation

피하조직에 투여된 수은과 카드뮴의 효소활성과 과산화지질에 미치는 영향

  • 하배진 (신라대학교 공과대학 생명공학전공)
  • Published : 2002.06.01

Abstract

Heavy metals like Mercury and Cadmium cause various kinds of toxicities in the organs of Liver and Kidney. To observe the results of toxicity in the liver, kidney, and serum when the rats were injected subcutaneously with HgCl$_2$ and CdC1$_2$ and sacrificed after 24 hours and 72 hours from the last injection, we measured variation of lipidperoxide values in rat liver homogenate, variation of aspartate aminotransferase and alanine aminotransferase in rat serum. Variation of lipidperoxide values in rat kidney homogenate and variation of BUN in rat serum. It was found that Mercury and Cadmium administered subcutaneously to the skin in the air could cause the damages of liver and kidney.

Keywords

Mercury;Cadmium;BUN;MDA;ALT;AST

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