Synthesis, Antinicrobial and Molluscicidal Activities of New Benzimidazole Derivatives

  • Nofal, Z.M. (Therapeutical Chemistry Dept. National Research Centre Dokki, Cairo, Egypt) ;
  • Fanmy, H.H. (Therapeutical Chemistry Dept. National Research Centre Dokki, Cairo, Egypt) ;
  • Mohamed, H.S. (Therapeutical Chemistry Dept. National Research Centre Dokki, Cairo, Egypt)
  • Published : 2002.02.01

Abstract

A series of Schiff's benzimidazole bases, thiosemicarbazides were synthesized, azole ring systems as 1,3,4-triazole, 1,3,4-oxadiazole were prepared. 1-Methylbenzimidazole incorporated to substituted dithio-carbamate, thiophenol, diethylamine via acetamido group were synthesized. A series of pyrimidinobenzimidazoles, triazinobenz-imidazoles, and 2-(acetonylamino)-1-methyl-benzimidazole were prepared. The antimicrobial and molluscicidal activities of some newly prepared compounds were carried out.

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