Insecticidal Activities of Bilobalide from Ginkgo biloba Leaves and its Derivatives

은행잎 유래 살충성분 bilobalide와 그 분해물의 살충활성

  • Yang, Eun-Young (National Institute of Agricultural Science & Technology, RDA) ;
  • Hong, Su-Myeong (National Institute of Agricultural Science & Technology, RDA) ;
  • Ahn, Young-Joon (Division of Applied Biology and Chemistry, College of Agriculture and Life Science, Seoul National University) ;
  • Kwon, Oh-Kyung (National Institute of Agricultural Science & Technology, RDA)
  • 양은영 (농업과학기술원 작물보호부 농약안전성과) ;
  • 홍수명 (농업과학기술원 작물보호부 농약안전성과) ;
  • 안용준 (서울대학교 응용생물화학부) ;
  • 권오경 (농업과학기술원 작물보호부 농약안전성과)
  • Published : 2001.03.30


This study was conducted to investigate insecticidal activities of Ginkgo biloba (L.) leaves-derived bilobalide and its hydrolysis and oxidation products against adults of Nilaparavata lugens Stal. To find out active insecticidal moiety of bilobalide, decomposed intermediates and derivatives of bilobalide were made by hydrolysis, oxidation, and acetylation. The structures of hydrolysis product by base and oxidation product by acid were identified as cyclopentenone analogues and trilactone sesquiterpene from dehydration of bilobalide, respectively. Insecticidal activities of the decomposed intermediates and the derivatives of bilobalide decreased in the order of bilobalide, monoacetate, ginkgolide C, oxidation product, diacetate, and hydrolysis product. Therefore, trilactone structure of bilobalide may be essential for its insecticidal activity.


Ginkgo biloba;bilobalide;insecticidal activity;hydrolysis product;oxidation product