Applied Chemistry for Engineering (공업화학)
- Volume 10 Issue 2
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- Pages.293-298
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- 1999
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- 1225-0112(pISSN)
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- 2288-4505(eISSN)
Optimization of Catalytic Reaction for Synthesis of 2-Methyl-4-methoxydiphenylamine
2-Methyl-4-methoxydiphenylamine 합성을 위한 촉매반응의 최적화
- Cho, Jeong-Woo (School of Chemical Engineering & Technology, Yeungnam University) ;
- Kim, Eun-Seok (School of Chemical Engineering & Technology, Yeungnam University) ;
- Kim, Kiseok (School of Chemical Engineering & Technology, Yeungnam University) ;
- Kim, Seong-Hoon (Department of Dyeing & Finishing, Kyungpook National University)
- Received : 1998.10.09
- Accepted : 1998.12.22
- Published : 1999.04.10
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32 3
Abstract
Reaction mechanism was elucidated and reaction condition were optimized for the catalytic reaction synthesizing 2-methyl-4-methoxy-diphenylamine (MMDPA) which is an intermediate of Fluoran heat-sensitive dyestuff. Reactants consisted of 2-methyl-4-methoxyaniline (MMA), 3-methyl-4-nitroanisole (MNA), and cyclohexanone, and 5 wt % Pd/C was used as a catalyst. Experiments were run in an open slurry reactor equipped with reflux condenser, and products were analyzed by means of GC/MS and NMR. MMDPA yield of 90 mole % could be obtained after reaction time of 8~10 hours under the optimal reaction conditions comprising the reaction mass composition of MMA : MNA : cyclohexanone = 1 : 2 : 150 based on MMA input of 0.01 gmoles in xylene solvent, reaction temperature of
Keywords
2-Methyl-4-methoxydiphenylamine;Rate-determining Step;Hydrogen-transfer reaction;Cyclohexanone
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Acknowledgement
Supported by : 한국과학재단
References
- U.S. patent 4,265,833 W. C. Friedrich;U. B. Heinz
- 일본특허 特開平 05-117,214 T. Akamatsu
- 일본특허 特開昭 60-51,157 Ricoh, Co., Ltd.
- Catalytic Hydrogenation R. L. Augustine
- Catalysis of Organic Reaction P. N. Rylander;H. Greenfield(eds.)
- European Patent Appl. EP 89,752 M. Kondo;H. Iwasaki;N. Kanda;M. Omatsu;H. Omura
- Hydrogenation Methods P. N. Rylander
- U.S. patent 5,545,752 T. Nagata;C. Kusuda;M. Wada
- U. S. patent 3,270,057 ICI
- U. S. patent 5,338,885 I. K. Otto;D. Gerhard;J. B. Hans
- U.S. patent 3,517,021 J. F. marsohik;P. N. Rylander
- 일본특허 特開昭 61-218,560 H. Ito;Y. Jinno;T. Nagata;I. Yokomachi