Antimicrobial Activities of Sesquiterpene Lactones Isolated from Hemisteptia lyrata, Chrysanthemum zawadskii and Chrysanthemum boreale

지칭개, 구절초 및 산국에서 분리한 Sesquiterpene lactones의 항균활성

  • Jang, Dae-Sik (Dept. of Agricultural Chemistry, Gyeongsang National University) ;
  • Park, Ki-Hun (Dept. of Agricultural Chemistry, Gyeongsang National University) ;
  • Lee, Jong-Rok (Dept. of Agricultural Chemistry, Gyeongsang National University) ;
  • Ha, Tae-Joung (Dept. of Agricultural Chemistry, Gyeongsang National University) ;
  • Park, Yun-Bae (Dept. of Biochemistry, Gyeongsang National University) ;
  • Nam, Sang-Hae (Dept. of Food Processing, Chinju National University) ;
  • Yang, Min-Suk (Dept. of Agricultural Chemistry, Gyeongsang National University)
  • Published : 1999.05.31

Abstract

In the bioactivity test of nine sesquiterpene lactons isolated from Hemisteptia lyrata, Chrysanthemum zawadskii and Chrysanthemum boreale, we investigated their antimicrobial activities against ten bacteria and six phytopathogenic fungi. Hemistepsin A and hemistepsin B isolated from H. lyrata and tulipinolide isolated from C. boreale exhibited strong antibacterial activity. In the antifungal test, hemistepsin B, angeloylcumambrin B, tigloylcumambrin B and costunolide showed broad activity. Both antibacterial and antifungal experiments exhibited quite clear specificity against microbial strains.