Isolation of Angiotensin Converting Enzyme Inhibitory Peptide from Beef Bone Extract Hydrolysate

  • Park, Eun-Hee (Department of Food Science & Technology, College of Agriculture, Chungnam National University) ;
  • Cho, Yong-Sik (Department of Food Science & Technology, College of Agriculture, Chungnam National University) ;
  • Song, Kyung-Bin (Department of Food Science & Technology, College of Agriculture, Chungnam National University)
  • Published : 1998.06.30

Abstract

Angiotensin converting enzyme (ACE) inhibitor was isolated from beef bone extract hydrolysate. After hydrolysis of beef bone extract with a commercial protease, ACE inhibitory peptide was purified by using ultrafiltration, gel permeation chromatography, and reverse-phase high pressure liquid chromatography. The purified ACE inhibitor was a pentapeptide, Gly-Pro-X-Gly-Pro.