Fine Needle Aspiration Cytology of Langerhans' Cell Histiocytosis in the Lymph Node - A Case Report -

림프절의 Langerhans세포 조직구증의 세침흡인 세포 소견 - 1예 보고 -

  • Kim, Eun-Kyung (Department of Pathology, Eulji University, Nowon Hospital) ;
  • Joo, Jong-Eun (Department of Pathology, Eulji University, Nowon Hospital)
  • 김은경 (을지대학교 노원병원 해부병리과) ;
  • 주종은 (을지대학교 노원병원 해부병리과)
  • Published : 1997.12.30


Langerhans' cell histiocytosis is a relatively rare disorder of children, characterized by abnormal proliferation of Langerhans' cells. It usually presents as multiple osteolytic lesion with lymphadenopathy or cutaneous manifestations. We experienced a case of Langerhans' cell histiocytosis involving bone and lymph node, diagnosed by fine needle aspiration cytology of the lymph node. The patient was a 10-year old girl with left inguinal lymphadenopathy. Fine needle aspiration cytology from the lymph node disclosed very cellular smear consisted of Langerhans' cells, eosinophils and lymphocytes. The Langerhans' cells had eccentric oval to reniform shape nuclei with grooving and abundant pale cytoplasm. The diagnosis was confirmed later by histologic study of bone lesion.