Separation and Activity Test of Antifungal Substance from C. japonica Extract

황련 추출물로부터 항균활성물질의 분리 및 활성 검정

  • Chung, Ill-Min (Dept. of Crops Science, Collage of Agriculture, Kon-Kuk Univ.) ;
  • Paik, Su-Bong (Dept. of Crops Science, Collage of Agriculture, Kon-Kuk Univ.)
  • 정일민 (건국대학교 식량자원학과) ;
  • 백수봉 (건국대학교 식량자원학과)
  • Received : 1996.10.11
  • Published : 1997.04.25

Abstract

This study was conducted to test antifungal activity and to separate bioactive compound using C. japonica extract which was shown the most effective control on the B. berengeriana, G. cingulata and P. expansum. $EC_{50}$ on the test pathogene of C. japonica extract was $400{\sim}500{\mu}g/mL$. Bioactive compound analyzed by TLC and HPLC method was identified as a kind of alkaloids, berberine, and the content was 81.14%.

Acknowledgement

Supported by : 건국대학교 생명과학연구원