Identification and Culture Conditon of an Actionomycetes Stranin Producing an Angiotensin Converting Enzyme Inhibitor

Angiotensin Converting Enzyme(ACE) 저해제를 생성하는 방선균 분리주의 동정 및 최적 발효조건

  • Moon, Seong-Hoon ;
  • Ha, Sang-Chul ;
  • Lee, Dong-Sun ;
  • Kim, Jong-Guk ;
  • Hong, Soon-Duck
  • 문성훈 (경북대학교 미생물학과) ;
  • 하상철 (한국과학기술연구원 부설 생명공학 연구소) ;
  • 이동선 (경북대학교 미생물학과) ;
  • 김종국 (경북대학교 미생물학과) ;
  • 홍순덕 (경북대학교 미생물학과)
  • Published : 1995.08.01


Identification of Actinomycetes isolate strain SH-8002, a producer of ACE inhibitor, based on procedures employed in the international Streptomyces project. The strain, designated as SH-8002, was identified as Streptomyces zoamyceticus SH-8002 based on its morphological, physiological, biochemical and chemotaxonomic characteristics. The ACE inhibitor produced by the strain was highly achieved in fermentation medium condition that was 1% soluble starch, 0.5% tryptone, 0.2% K$_{2}$HPO$_{4}$, 0.2% CaCO$_{3}$, 0.1% NaCl, pH 8.0 at 30$\circ$C for 144 hrs.


Angiotensin converting enzyme inhibitor;identification;Strptomyces zoamyceticus SH-8002;optimum fermentation condition


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