Composition and Distribution of Intestinal Microbial Flora in Korean

한국인의 장내 균총 조성 및 분포

  • 지근억 (한림대학교 식품영양학과)
  • Published : 1994.10.01


Intestinal microbial flora comprise one third of the large intestinal contents in human. They play a significant effects through beneficial and harmful action on the human health. This is the first study which examined the composition of the microflora of the general population in Korea. Bacteroides, Bifidobacterium, Eubacterium, Peptostreptococcus, Lactobacillus, Streptococcus, Escherichia coli, Staphylococcus, Clostridium perfringens, total aerobic bacteria and total anaerrobic bacteria were counted using various selective and non-selective media. Among the bacteria studied the number of Bifidobacterium were greatest in breast-fed infants(30-90 days old), whereas Streptocuccus and Bifidobacterium in bottle-fed infants. In 20-40 age group Bacteroides were predominant followed by Bifidobacterium and Eubacterium. In early group(over 65 years old) Bacteroides were predominant followed by Eubacterium and bifidobacterium. The frequency and number of Cl. perfringens were highest in dlderly group. These results confirm that the microfloral pattern in large intestine change during the life cycle of humans.


  1. J. Appl. Bacteriol. v.70 The control and consequences of bacterial fermentation in the human colon Cummings,J.H.;G.T.Macfarlane
  2. Modern Nutrition in Health and Disease The roles of the intestinal flora Goldin,B.R.;A.H.Lichtenstein;S.L.Gorbach;Maurice,E.S.(ed.);V.R.Young(ed.)
  3. 腸內細菌學 光岡知足
  4. A color Atlas of Anaerobic Bacteria(2nd ed.) Mitsuoka,T.
  5. 1992년도 춘계학술 발표대회 초록집 한국인 유아의 장내 세균 분포;미생물학회 특별강연 지근억
  6. J. Appl. Bacteriol. v.68 Detection of Bifidobacterium species by enzymatic methods Chevalier,P.;D.Roy;P.Ward
  7. 한국산업미생물학회지 v.22 유제품으로부터 Bifidobacteria의 선발 및 계수를 위한 선택배지 신명수;이정준;서인영;나석환;백영진
  8. 대한민국 특허 출원 제7750호 개량된 Bifidobacteria의 선택배지 지근억;이세경;김인희
  9. 한국식품과학회지 v.26 한국인의 분변으로부터 Bacteroides를 분리하기 위한 선택배지 조사 지근억;이세경;김인희
  10. 한국미생물학회지 v.22 인체 분변으로부터 Eubacterium을 분리하기 위한 선택배지 지근억
  11. Bergey’s manual of Determinative Bacteriology v.2 Sneath,P.H.A.;S.M.Nicholas;M.E.Sharpe;J.G.Holt
  12. 한국식문화학회지 v.7 서울 및 경기지역 유아의 수유 및 이유에 관한 실태 조사 손경희;윤선;이영미;민성희;전주혜
  13. 한국영양학회지 v.27 강원도 춘천지역 유아의 이유 실태 조사연구 이정수;이상호;주진순
  14. 한국낙농학회지 v.6 한국 유아의 익변중 Bifidobacterium의 분포 박경식;강국희