Fine Needle Aspiration Cytology of Ki-1 Positive Large Cell Lymphoma- A Case Report -

Ki-1양성 대세포림프종의 세침흡인 세포학적 소견 - 1예 보고 -

  • Kwon, Kye-Hyun (Department of Anatomical Pathology, Soonchunhyang University Hospital) ;
  • Kwak, Jeong-Ja (Department of Anatomical Pathology, Soonchunhyang University Hospital) ;
  • Jin, So-Young (Department of Anatomical Pathology, Soonchunhyang University Hospital) ;
  • Lee, Dong-Wha (Department of Anatomical Pathology, Soonchunhyang University Hospital)
  • 권계현 (순천향대학 부속병원 해부병리과) ;
  • 곽정자 (순천향대학 부속병원 해부병리과) ;
  • 진소영 (순천향대학 부속병원 해부병리과) ;
  • 이동화 (순천향대학 부속병원 해부병리과)
  • Published : 1993.12.30

Abstract

Ki-1 lymphoma is a sort of high grade large cell lymphoma and defined on the basis of the reactivity of the tumor cells with monoclonal antibody Ki-1. On fine needle aspiration cytology, the reported case is rare and the differential diagnosis is not easy, especially from undifferentiated carcinoma and Hodgkin's lymphoma. We experienced a case of fine needle aspiration cytology of Ki-1 positive large cell lymphoma in a 61-year old male patient. Fine needle aspiration cytology from the cervical lymph node disclosed hypercellular smears with large single cells on polymorphous lymphoid background. The tumor cells had abundant dense cytoplasm and large nuclei with Irregular profiles. Although most cells were mononuclear binucleated and multilobed/multinucleated cells were also seen Immunohistochemistry was done and revealed strong positive staining for Ki-1 antigen.