Inhibition Effect of Against Angiotensin Converting Enzyme of Flavan-3-ols isolated Korean Green Tea

한국산 녹차로부터 분리한 Flavan-3-ol 화합물의 Angiotensin Converting Enzyme 저해 효과

  • Cho, Young-Je (Department of Food Science and Technology, Yeungnam University) ;
  • An, Bong-Jeun (Department of Herb and Food Science, Tongguk Junior College) ;
  • Choi, Cheong (Department of Food Science and Technology, Yeungnam University)
  • 조영제 (영남대학교 식품가공학과) ;
  • 안봉전 (동국전문대학 약용식품과) ;
  • 최청 (영남대학교 식품가공학과)
  • Published : 1993.06.01

Abstract

For the Purpose of utilizing tannins in the functional foods and crude drugs, the enzyme inhibition of tannins isolated from Korean green tea were determined. Acetone extract from Korean green tea showed inhibition effect against the angiotensin converting enzyme. The galloyl tannins showed higher inhibition activity against angioteosin converting enzyme than the nongalloyl tannins. In terms of stereo isomers, (-)-epicatechins had higher inhibition activity than the (+ )-catechins. The synergistic activity was also observed. Tannins isolated from Korean green tea appeared to be incompetitive inhibitor against the angiotensin converting enzyme.