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INSULIN RESPONSIVENESS TO GLUCOSE AND TISSUE RESPONSIVENESS TO INSULIN IN SOWS, SHEEP AND PIGS

  • Sano, H. (Faculty of Animal Science, Kitasato University) ;
  • Terashima, Y. (Faculty of Animal Science, Kitasato University)
  • Received : 1990.07.27
  • Accepted : 1990.11.17
  • Published : 1991.03.01

Abstract

Insulin responsiveness to glucose and tissue responsiveness to insulin, using the hyperglycemic clamp and the hyperinsulinemic euglycemic clamp techniques, were compared among cows, sheep and pigs. The plasma insulin concentrations during the hyperglaycemic clamp period were highest (p < 0.05) in cows, followed by sheep and pigs. The glucose infusion rate in the hyperinsulinemic euglycemic clamp technique was greater (p < 0.01) in pigs than in cows and sheep. These results suggest responsiveness to insulin is higher in pigs than in cows and sheep.

Keywords

Insulin;Glucose Clamp;Cow;Sheep;Pig

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