Preparation of Poly(hydroxypropyl methacrylate) Membraney by Sintering Method and Its Permeation Characteristics

소결공정에 의한 Poly(hydroxypropyl methacrylate) Membrane 제조와 그의 투과특성에 관한 연구

  • Shim, Jyong-Sup (Department of Chemical Technology, Seoul National University) ;
  • Lee, Dong-Kweon (Department of Chemical Technology, Seoul National University) ;
  • Hong, Jae-Min (Department of Chemical Technology, Seoul National University)
  • 심정섭 (서울대학교 공과대학 공업화학과) ;
  • 이동권 (서울대학교 공과대학 공업화학과) ;
  • 홍재민 (서울대학교 공과대학 공업화학과)
  • Received : 1990.11.27
  • Published : 1990.12.31

Abstract

Poly(hydroxypropyl methacrylate) membranes and matrix devices having tertiary amine moiety were prepared by sintering method, and their permeation characteristics were investigated. The water content of this membrane was increased with decreasing the pH of the medium. The permeability of this membrane was increased with decreasing the sintering pressure. Using sintered matrix device 'burst effect' was found at the early stage, and initial insulin release of glucose oxidase immobilized matrix device could be controlled by glucose concentration of the solution.

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