Studies on the Pharmacological Actions and Biologically Active Components of Korean Traditional Medicines(VII) -On the Anticancer Macromolecular Substances from Duchesnea indica Herba-

한국전통전통 생약의 약리작용과 활성물질에 관한 연구(VII) -사매의 항암성 고분자물질-

  • Lee, Ihn-Rhan (College of Pharmacy, Ewha Womans University) ;
  • Hahn, Seung-Hye (College of Pharmacy, Ewha Womans University) ;
  • Han, Yong-Nam (Natural Products Research institute, Seoul National University) ;
  • Jeong, Ga-Jin (Department of Microbiology, College of Natural Sciences, Seoul National University)
  • 이인란 (이화여자대학교 약학대학) ;
  • 한승혜 (이화여자대학교 약학대학) ;
  • 한용남 (서울대학교 생약연구소) ;
  • 정가진 (서울대학교 자연과학대학)
  • Published : 1990.06.30

Abstract

This study was conducted to further purify and characterize a polysaccharide fraction from whole parts of Duchesnea indica (Andr.) Focke, which was previously reported to show an antitumor activity by us. Mild acid-treatment of the fraction by 5% acetic acid yielded three subtractions (Fr. A,B and C) on a Sephadex G-25. Fr. A was composed of uronic acid, hexose, pentose and phenolic substance, Fr. C mainly phenolic substance, and Fr. B contained hexose. All three fractions exhibited colony stimulating factor activity.