Synthesis of Sulfonylurea Derivatives by Oxalylchloride

Oxalylchloride를 이용한 Sulfonylurea계 유도체 합성에 관한 연구

  • Published : 1989.12.30


An alternative method for the synthesis of sulfonylurea derivatives, some of which considered to be a new recommendable herbicides, with oxalylchloride was investigated. Sulfonamides read with oxalylchloride to sulfonyloxamoylchlorides, which convert easily under pyrolysis to sulfonylisocyanates. The isocyanates react further with amines to yield corresponding sulfonylurea derivative quantitatively.