Studios on the Glutamic Acid Production by an Alkalophilic Bacterium

알칼리성 세균에 의한 글루탐산 생산에 관한 연구

  • Cho, Kae-Ran (College of Pharmacy, Ewha Womans University) ;
  • Lee, Kang-Man (College of Natual Sciences, Ewha Womans University) ;
  • Bae, Moo (College of Natual Sciences, Ewha Womans University)
  • 조계란 (이화여자대학교 약학대학) ;
  • 이강만 (이화여자대학교 약학대학) ;
  • 배무 (이화여자대학교 자연과학대학)
  • Published : 1989.12.01


An alkalophilic bacterium isolated from compost was selected, identified and tested for the production of glutamic acid from ammonium fumarate. The bacterium was closely related to Bacillus brevis. The conditions for glutamic acid production were pH 8.0, 2% fumaric acid, and 0.8% nutrient broth. The mechanism of glutamic acid formation in this strain was postulated as following scheme. (1) Ammonium fumarate longrightarrow Aspartic acid (2) Aspartic acid + $\alpha$-Ketoglutaric acid longrightarrow Glutamic acid + Oxaloacetic acid.