Studies on the Pharmacological Actions and Biologically Active Components of Korean Traditional Medicine (VI). -Tannins from Duchesnea indica-

한국 전통생약의 약리작용과 활성물질에 관한 연구(VI). -사매의 Tannin계 물질-

  • Lee, Ihn-Rhan (College of Pharmacy, Ewha Womans University) ;
  • Wee, Seung-Won (College of Pharmacy, Ewha Womans University) ;
  • Han, Yong-Nam (Natural Products Research Institute, Seoul National University)
  • 이인란 (이화여자대학교 약학대학) ;
  • 위승원 (이화여자대학교 약학대학) ;
  • 한용남 (서울대학교 생약연구소)
  • Published : 1989.06.30

Abstract

This study was conducted to purify and characterize a polysaccharide fraction from whole parts of Duchesnea indica (Andr.) Focke, which was previously reported to show an antitumor activity by us. The plant was extracted with 5% ethanol for 3 days in the room temperature. The extract was dialyzed by 5% ethanol, and then concentrated by extraction with $excess\;_N-butanol$, followed by gel filtration named Fr. a and b. Each was composed of gallic acid, hexose, pentose, uronic acid and protein, indicating that both fractions were tannic polysaccharide containing protein. Heat treatment of them yielded gallic acid less polysaccharides. They showed a colony stimulating factor activity.