Effect of First-Aid Drugs on Internal Contamination of Radiostrontium

방사성(放射性) 스트론듐의 체내오염(體內汚染)에 대한 응급처치제(應急處置劑)의 효과(效果)

  • Chung, In-Yong (Korea Cancer Center Hospital Korea Advavced Energy Research Insttitute) ;
  • Kim, Tae-Whan (Korea Cancer Center Hospital Korea Advavced Energy Research Insttitute) ;
  • Chin, Soo-Yil (Korea Cancer Center Hospital Korea Advavced Energy Research Insttitute)
  • 정인용 (원자력병원 한국에너지연구소) ;
  • 김태환 (원자력병원 한국에너지연구소) ;
  • 진수일 (원자력병원 한국에너지연구소)
  • Published : 1989.06.20

Abstract

To obtain the basic data for protective roles and first-aid of radiation hazard, the present studies were carried out to evaluate the decontamination of radiostrontium by the First-Aid drugs. Each mouse was administered intraperitoneally dose of sodium alginate 5mg, $CaNa_3DTPA$ 8.4mg and saline 5ml following the internal contamination with 1 $\mu$Ci of strontium as $^{85}SrCl_2$. $^{85}Sr$ was determined by the radioactivity of body burden, urinary excretion, fecal excretion and organ distribution by Ge-detector and MCA. The results are summarized as follows. 1. Effective half life on whole body retention $^{85}Sr$ was determined at 33 hours. 2. The decontamination effect of First-Aid durgs on the body $^{85}Sr$ burden were increased $CaNa_3DTPA$ (4.7 times), sodium alginate (1.7 times) and saline (2.4 times) respectively. 3. Strontium were excreted through urine (35.4%), feces (64.4%) and other (0.2%). But on the $^{85}Sr$ excretion routes following First-Aid drugs treatment, strontium-85 mainly were excreted through urine after $CaNa_3DTPA$ and saline treatment, and was excreted through feces after sodium alginate treatment. 4. The organ distribution of strontium-85 is vertebra, femur, sternum and liver in order Finally, the extrapolations from these data to victims were suggested that the rapid administration of $CaNa_3DTPA$, sodium alginate and saline simultaneously were markedly increased the decontamination effects on the internal contamination of radiostrontium.

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