Inhibitory Substance Produced by Aspergillus sp. on the Snake Proteinase - Culture Conditions for the Production of Inhibitor -

Aspergillus 속 균주가 생성하는 사독 proteinase에 대한 저해물질- 저해물질의 생산조건 -

  • Nam Joo Hyun (Department of Food Technology, Taegu Technical Junior College) ;
  • Jung Hwn Seu (Department of Microbiology, College of Natural Science, Kyungpook National University)
  • Published : 1987.04.01

Abstract

Aspergillus sp. MK-24 was cultured at 3$0^{\circ}C$ in the medium consisting of 2% glucose, 0.2% NaNO$_3$, 0.02% $K_2$HPO$_4$, 0.02% MgSO$_4$ 7$H_2O$, 0.02% KCl, and at initial pH of 5.0. The production of the inhibitor on venom proteinase reached to the maximum in 7 days. Sodium nitrate or potassium nitrate as a nitrogen source was favorable. The production of inhibitor was not affected by the addition of most of the inorganic salt used but depressed by lead, zinc, cobalt, mercuric or silver salts.

Keywords

Snake proteinase;inhibitor production