Hemagglutination of Hantaan and Seoul Viruses

한탄바이러스와 서울바이러스의 혈구응집반응

  • Seong, In-Wha (Department of Microbiology, Medical College, Korea University) ;
  • Song, Ki-Joon (Department of Microbiology, Medical College, Korea University) ;
  • Lee, Ho-Wang (Department of Microbiology, Medical College, Korea University)
  • 성인화 (고려대학교 의과대학 미생물학교실) ;
  • 송기준 (고려대학교 의과대학 미생물학교실) ;
  • 이호왕 (고려대학교 의과대학 미생물학교실)
  • Published : 1986.06.30

Abstract

The hemagglutination activities of Hantaan virus and Seoul virus were demonstrated. The hemagglutinins were prepared by sucrose-acetone extraction method from suckling mouse brains infectecd with Hantaan and Seoul viruses. Hemagglutination of goose erythrocytes by these viral hemagglutinins was pH dependent in phosphate buffer system. Hantaan and Seoul viruses were distinguished by pH range of hemagglutination. 76/118 and 79/90 strains of Hantaan virus showed hemagglutination at the range of pH 5.75-6.4 and the optimal pH was 5.75 with the titer of 1:512 in 76/118 and 1:256 in 79/90. In contrast, KSNUSD 84/34 strain of Seoul virus revealed hemagglutination at the range of pH 6.2-6.4 and the optimal pH was 6.4 with the titer of 1 : 64.