Diagnostic Value of Serum Beta-hCG Measured by EIA in Suspected Ectopic Pregnancy

EIA로 측정한 혈청 ${\beta}$-hCG치의 자궁외 임신에 대한 진단적 가치

  • Park, Yoon-Ki (Department of Obstetrics and Gynecology College of Medicine, Yeungnam University) ;
  • Kim, Jong-Wook (Department of Obstetrics and Gynecology College of Medicine, Yeungnam University) ;
  • Lee, Tae-Hyung (Department of Obstetrics and Gynecology College of Medicine, Yeungnam University) ;
  • Park, Wan-Seok (Department of Obstetrics and Gynecology College of Medicine, Yeungnam University) ;
  • Lee, Sung-Ho (Department of Obstetrics and Gynecology College of Medicine, Yeungnam University) ;
  • Chung, Wun-Yong (Department of Obstetrics and Gynecology College of Medicine, Yeungnam University)
  • 박윤기 (영남대학교 의과대학 산부인과학교실) ;
  • 김종욱 (영남대학교 의과대학 산부인과학교실) ;
  • 이태형 (영남대학교 의과대학 산부인과학교실) ;
  • 박완석 (영남대학교 의과대학 산부인과학교실) ;
  • 이승호 (영남대학교 의과대학 산부인과학교실) ;
  • 정원영 (영남대학교 의과대학 산부인과학교실)
  • Published : 1985.06.30

Abstract

Thirty-four patients with suspected ectopic pregnancy whose serum hCG levels had been measured by beta-hCG EIA before surgery were evaluated retrospectively. The results were as follows: 1. Final diagnosis of thirty-four patients with suspected ectopic pregnancy comprised twenty- eight tubal pregnancy, five ruptures of hemorrhagic corpus luteum and, one tubo-ovarian abscess. One of the five patients with rupture of hemorrhagic corpus luteum was accompanied by missed abortion. 2. Range of serum hCG levels in twenty-eight patients with tubal pregnancy was 59-21,980 mIU/ml and that of four patients with rupture of hemorrhagic corpus luteum and one patient with tubo-ovarian abscess was 0.6-6.6mIU/ml. Serum hCG level of a patient with rupture of hemorrhagic corpus luteum who was accompanied by missed abostion was 200 mIU/ml. 3. Serum hCG levels in twenty-two of twenty-eight patients with tubal pregnancy were lower than 3,000 mIU/ml. Low serum hCG level below 100mIU/ml and high serum hCG level above 6,500 mIU/ml were noticed in four and six patients with tubal pregnancy, respectively. 4. Mean serum hCG levels (${\pm}SD$) of twelve patients with tubal pregnancy who had intra-abdominal free blood of less than 500ml and sixteen patients with tubal pregnancy who had intra-abdominal free blood of more than 500ml were 4,131 (${\pm}7,801$) mIU/ml and 3,208 (${\pm}5,081$) mIU/ml, respectively. There was no statistical difference in the mean level of serum hCG between both group (P>0.05). 5. Mean serum hCG levels (${\pm}SD$) of thirteen patients with unruptured tubal pregnancy and fifteen patients with ruptured tubal pregnancy were 2,628 (${\pm}5,448$) mIU/ml and 4,449 (${\pm}6,938$) mIU/ml, respectively. Mean level of serum hCG was statistically higher in ruptured tubal pregnancy (P<0.01). 6. Positive rate of urine pregnancy test in the diagnosis of ectopic pregnancy was 64% (16/25) and mean range of serum hCG level of nine patients with false negative result were 353 mIU/ml and 59-933 mIU/ml.

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