- Volume 10 Issue 1
An Experimental Study on the Effects of Low Power Density Laser (ASGA) on the Wound Healing of Rat Tongue and Skin
저출력 레이저 광선이 백서연조직 창상 치유에 미치는 영향에 관한 실험적 연구
- 김기석 (서울대학교 대학원 치의학과 구강진단학 교실) ;
- 김영구 (서울대학교 대학원 치의학과 구강진단학 교) ;
- 정성창 (서울대학교 대학원 치의학과 구강진단학 교실)
- Published : 1985.12.01
In order to study the effects of the low power density laser (AsGa) on the wound healing of tongue and skin, thirty two healthy rats were anesthetized with pentothal. The tongue wound, approximately 1 mm in depth and 2mm in diameter, was created on the anterior of the tongue and the skin wound, approximately, 2mm in depth and 6-8mm in diameter, was created on the back of rat with the tip of small rongeur forcep. Wounds of experimental groups were irradiated with AsGa laser (Stomalaser, SEDATELEC Co., France) every other day by ninth day. The areas of wounds were measured at 1, 3, 5, 7, 9 days after wounding and the specimens were sectioned, stained, and observed with light microscope. The results were as follows : 1. In the AsGa laser irradiated wound of tongue, the epithelial and fibroblastic regeneration were accelerated when compared with controls. 2. In the AsGa laser irradiated wound of skin, the epithelial and fibroblastic regeneration were accelerated when compared with controls. 3. When the wound areas were compared, there was a significant difference between control group and experimental group (P < 0.01: 2-Way NOVA).