Effects of Radiation on the Chromosomes in Bone Marrow Cells of the Mouse

방사선(放射線)이 생쥐 골수세포(骨髓細胞)의 염색체(染色體)에 미치는 향영(響影)

  • Kim, Yung-Jin (Department of Biology, Chungnam National University) ;
  • Kim, Jong-Bong (Department of Biology, Hyosung Women's University)
  • 김영진 (충남대학교 생물학과) ;
  • 김종붕 (효성여자대학교 생물학과)
  • Published : 1985.12.20

Abstract

To study the relationships among the frequency of chromosomal aberration induced by radiation, mouse age at the time of exposure and elapsed time after the irradiation, the 40, 150 and 300 day old mice were irradiated by gamma rays to 200 rad of acute whole body doses. The bone marrow chromosomes were observed in 8 experimental groups such as 1, 2, 3, 4, 8, 16, 30, 60 and 90 days after irradiation. In the 40 day old mice the frequencies of cell with chromosomal aberration were 53.0%, 21.5%, 8.4%, 8.4%, 12.0%, 8.0%, 7.0% and 5.0% in 8 experimental groups, in the 150 day old mice 32.5%, 12.1%, 10.5%, 12.8%, 0.03%, 9.7%, 7.0% and 4.2%. The 300 day old mice showed that the frequencies of cells with chromosomal aberration were 27.7%, 13.6%, 9.0%, 9.3%, 13.3%, 14.4%, 7.5% and 9.5% in each experimental group. There were tendencies that the frequencies of cell with chromosomal aberration were higher in the young mice than the old ones within 2 days after the irradiation but in the old mice than the young ones after 4 days.

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